Nanomedicine, Volume IIA: Biocompatibility
© 2003 Robert A. Freitas Jr. All Rights Reserved.
Robert A. Freitas Jr., Nanomedicine, Volume IIA: Biocompatibility, Landes Bioscience, Georgetown, TX, 2003
Index A-Z
A
a?actinin, 116
a ?amylase, 41
a1?antitrypsin, 39
a1?proteinase inhibitor, 113
a2?macroglobulin, 39
A2E, 159
aB?crystallin, 153
ABO blood group, 31
Abrasive dermatitis, 126
Abrin, 1
Abscess, 66, 74
Acanthite, 160
Acetylcholine, 57, 59, 61, 121
Acidosis, 43, 120
Acoustic, 11, 112, 125, 131, 134, 152, 153
Acrylamide, 13, 17
ACTH, 45
Actin, 18, 51, 60, 78, 96, 115, 116, 117, 118, 119, 122, 123, 136, 142, 151,
152, 153, 161
Active adhesion, 64
Acupuncture, 126
Adamantane, 28, 29, 38, 43, 45, 54, 116, 123
Adams, Ann L., 12
ADCC, 20
Adcock, Jamie L., 69
Adenylate cyclase, 112, 115, 120, 131
Adenylyl cyclase (AC), 131
Adherent bacteria, 11, 14
Adherent cell, 17, 51, 63
Adhesion, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 38, 39, 49, 50, 51,
52, 54, 58, 60, 63, 64, 69, 70, 71, 78, 79, 85, 87, 88, 101, 115, 116, 119,
130, 132, 135, 136, 140, 141, 142, 143, 145, 147, 150, 151, 154
Adhesion antennae, 143
Adhesion Dynamics model, 13
Adhesion force, 136, 154
Adhesion inhibit, 14, 39, 52
Adhesion of enzymes, 69
Adhesion protein, 19, 50, 54
Adhesion strength, 12, 136
Adhesion surface, 52
Adhesion molecule, 140
Adhesion protein, 50
Adhesioregulation, 19
Adhesioregulatory, 14, 18, 19, 24, 87
Adhesive interactions with implant surfaces, 12
Adhesive nanorobot, 16
Adjuvant, 19, 28, 41, 54, 58, 66, 80, 85, 100, 119
ADME, 54
ADP, 38, 59, 144
Adrenal cortex, 32
Adrenaline, 139; see also epinephrine
Adrenergic, 160
Advanced Surface Technologies, 13
AED, 112
Aerobic dancing, 138
Aerobot, 126
Affinity, 13, 14, 16, 21, 24, 25, 39, 41, 44, 50, 51, 57, 60, 69, 75, 101, 103,
146, 148
Afipia, 119
Aflatoxin, 116
AFM (atomic force microscope), 4, 8, 10, 12, 15, 76, 140
Agarose, 23
Agenesis, 45
Agglutinate, 1, 159
Agglutination, 27, 34
Aggregation, 13, 14, 38, 39, 40, 73, 101, 116, 132, 137, 139, 140, 141, 142,
147, 154, 159
Aggregation inhibitor, 39, 40
Aggregations of macrophages, 65, 99
Aggressin, 113, 115, 120
Agonist, 29, 59, 113, 115, 131
Agranulocyte, 98, 140
Air?blood barrier, 101
Ajayan, Pulickel, 56
Akagawa, Y., 77
Al, 50, 83
Al2O3, 9, 75, 76, 78, 79, 80, 145
Albumin, 12, 13, 14, 18, 19, 38, 39, 50, 51, 52, 61, 62, 63, 69, 71, 75, 76,
86, 87, 94, 100, 101, 121, 158
Albunex, 158
Alcian blue, 112
Aldehyde, 58
Algae, 112, 144
Alginate, 117
Alimentary, 1, 105, 106, 122, 155
Alippi, Adriano, preface
Alkaline phosphatase (ALP), 51, 78, 79, 141
Alkaloid, 1, 42, 43
Alkanethiol, 14, 18
Allen, L., 108
Allen, M., 52
Allergen, 28, 40, 41, 66, 73
Allergic and other sensitivity reactions, 7, 33, 40, 41, 42, 55, 66
Allergology, 41
Allergy(-ies), 40, 41, 42, 71, 107
Alloantigen, 31
Allodynia, 125, 126
Allogeneic, 31, 32, 115
Allograft, 29, 31, 32
Alloknesis, 125
Alloplast, 72
Allosteric control, 16
Allotypic, 26
ALS, 61, 149; see also amyotrophic lateral sclerosis
Alternative pathway, 22, 23, 24, 25, 33
Altitude?adapted, 158
Alumin, 75
Alumina (aluminium oxide), 8, 9, 13, 23, 38, 41, 45, 46, 49, 54, 64, 72, 75,
76, 77, 78, 79, 80, 81, 90, 100, 107, 122, 138, 145, 148, 157, 160; see also
sapphire
Alumina particle(s), 75, 79, 80, 107, 148, 157
Aluminosilicate, 104, 107
Aluminum, 5, 8, 41, 46, 75, 76, 78, 80, 81, 89, 122, 138
Aluminum silicate, 41
Alveolar epithelial cells, 5, 67
Alveolar macrophage?derived growth factor, 160
Alveolitis, 4, 5, 6, 67, 68
Alzheimer’s disease, 46, 61, 149
Amantadine, 54, 115, 120
Ambroxol, 41
Ambulating, 130, 151, 152
Ambulation, 142
Amebiasis, 43
American College of Governmental Industrial Hygienists, 5
Amine, 9, 15, 17, 28, 56, 58, 84
Amino acid(s), 16, 17, 21, 23, 25, 26, 28, 33, 59, 88, 89, 123, 143, 153
Aminodextran, 101
Aminoglycoside, 11, 97, 142
Aminophylline, 106
Ammonia, 42, 119
Ammonium acetate, 115
Ammonium chloride, 119
Amnion, 33
Amniotic, 17, 33, 156
Amoeba, 43, 99, 100, 119, 161
Amoeba proteus, 136, 161
Amorphous carbon particle, 45, 65
AMPA, 61
Amphipathic coating, 148
Amphipathic drug, 139
Amphiphile, 94
Amphiphysin II, 117
Amphoteric, 75, 145
Ampicillin, 115
Amyloid, 61, 123, 159
Amyloidosis, 153
Amyotrophic lateral sclerosis, 61, 149, 152; see also ALS
Anaerobic bacteria, 10
Analgesia, 126
Anaphylactic(-oid) reaction, 24, 40, 72
Anaphylactic shock, 40, 43
Anaphylatoxin, 24, 25, 40
Anaphylatoxin inactivator (AI), 25
Anaphylaxis, 40, 41
Anastomose, 72, 94, 98
Anastomotic, 133
Andrade, J.D., 14
Andrew, Alex M., preface
Andrievsky, G., 60
Anemia, 95, 128, 135, 138, 149, 158
Anergic, 31, 120
Aneurysm, 72, 98, 129, 133, 135
Angelica, Amara D., preface
Angelucci, Rocky, preface
Angina pectoris, 123
Angioedema, 40
Angiogenesis, 36, 111
Angioplasty, 15, 17, 93, 132, 133
Angiotensin, 131
Anhydrobiotic, 143
Animal dander, 40
Anion, 17, 38, 49, 84, 98, 100, 112, 116, 119, 145
Anophthalmic, 72
Antagonist, 25, 29, 36, 39, 41, 43, 46, 57, 60, 61, 85, 86, 87, 110, 112, 113,
131
Anthracosis, 5
Anthrax, 115, 120
Anthrax toxin edema factor, 115, 120
Anti?antibodies, 30
Anti?apoptotic(-sis), 60, 153
Anti?emetic, 46
Anti?idiotypic antibody(-ies), 30
Anti?mRNA, 143
Anti?RNA antibody, 142
Antiapoptotic(-sis), 60, 85
Antibacterial, 44, 60, 83
Antibiotic, 9, 10, 11, 44, 72, 86, 88, 113, 115, 132, 144, 148
Antibody(-ies), 10, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33,
34, 36, 39, 40, 41, 43, 45, 46, 58, 59, 63, 66, 79, 82, 84, 87, 88, 89, 95,
99, 110, 112, 113, 114, 115, 116, 117, 120, 121, 142, 146; see also immunoglobulin
Antibody binding site, 28
Antifungal, 112
Antigen, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35,
40, 41, 45, 66, 88, 98, 99, 113, 114, 117, 120, 136, 146
Antigen binding site, 26, 27
Antigen?antibody complex, 23, 24, 28, 40, 99
Antigenic binding site, 26
Antigenic particle, 21, 27
Antigens, 19, 21, 22, 23, 26, 27, 28, 29, 30, 31, 32, 34, 41, 63, 71, 88, 96,
100, 114
Antihistamine, 41, 43
Antilymphocyte globulin (ALG), 30
Antimicrobial, 20, 44, 60, 85
Antimitotic, 30, 132
Antiphospholipid syndrome (APS), 82
Antiprion, 85
Antipyretic, 46
Antisense, 82, 85, 113
Antithrombin III, 39
Antitrypanosomal, 86
Antiviral, 28, 54, 60, 85
Aortic endothelial cell(s), 63, 130, 147
Aortic rupture, 72, 132
APC, 21, 40, 88, 89
Apheresis, 7
APO?1, 32
Apoptosis, 15, 20, 32, 33, 35, 60, 61, 67, 80, 85, 87, 98, 100, 109, 116, 118,
120, 121, 122, 130, 131, 132, 133, 135, 141, 142, 145, 149, 152, 153, 161
Apoptotic, 20, 34, 60, 61, 80, 82, 98, 103, 112, 116, 120, 130, 142, 148, 153
Aptamer, 25, 82
Aquaporin, 148
Arabinose, 86
Arachidonic acid, 36, 41, 45, 120
Area postrema, 43, 87
ARF, 115
Arnold, G.E., 73
Arp2/3 complex, 116
Arterial dissection, 137
Arteriovenous fistula, 130, 134, 138
Arteriovenous shunt, 10, 96, 97
Artery dissection, 134
Artery erosion, 134
Arthropathy, 46
Arthroplasty, 45, 63
Arthus reaction, 41
Artificial binding site, 19, 112
Artificial biological phagocytes, 121, 122
Artificial glycocalyx, 13
Artificial heart valve, 7, 8, 52, 62, 138
Artyuhov, Igor, preface
Arvidson, K., 77, 81
Asbestos, 5, 47, 55, 56, 108, 123, 160
Asbestos particle, 160
Ascites, 157
Asialoglycoprotein, 17
Aspergillosis, 121
Aspirin, 36, 40, 46, 88
Asplenic, 95
Asters, 150
Asthma, 6, 40, 41
Astrocyte, 66, 67, 85, 86, 104, 135
Astrocytic, 105
Astrocytosis, 73
Astroglioma, 115
AT&T Bell Laboratories, 4
Atelectasis, 45
Atherectomy, 133
Atherosclerosis(-tic), 98, 132, 137, 140, 159, 160
Atomic Adsorption Spectroscopy (AAS), 54
Atomic force microscope, see AFM
ATP, 119, 120, 130, 144, 147, 151, 153
ATP synthase (ATPase), 59, 119, 144
Atrial natriuretic peptide, 139
Ausman, Kevin D., preface, 55, 56
Austenite(-ic), 52, 83
Autoantigen, 32
Autocatalytic, 150
Autoimmune disease, 21, 23, 30, 32, 71, 82, 120, 121
Autoimmunity, 29, 32
Autolysis, 149
Autophagy, 153
Autosomal, 42
Avoid phagocytic binding and activation, 114
Avoid phagocytic contact, 112
Avoid phagocytic recognition, 114
Axon, 85, 150, 151, 152
Azathioprine, 30, 113
Azelastine, 42, 112
B
b?lactoglobulin, 75, 76
Ba, 23
Babesiosis, 138
Bacillus anthracis, 88
Bacillus carbophilus Kasumi, 64
Bacillus subtilis, 112
Bacitracin, 115
Bacon, Francis, quotes
Bacteremic, 158
Bacteria, 4, 10, 11, 13, 14, 15, 20, 21, 22, 23, 24, 25, 29, 31, 32, 33, 34,
43, 44, 60, 64, 71, 79, 82, 88, 89, 95, 96, 98, 99, 101, 102, 103, 106, 108,
111, 112, 113, 114, 117, 118, 119, 122, 127, 129, 132, 142, 143, 144, 145, 146,
149, 161
Bacteria adhesion, 71
Bacteria that phagocytose, 145
Bacteria?rich colon, 127
Bacterial, 3, 10, 11, 14, 19, 20, 22, 23, 25, 26, 27, 31, 32, 34, 36, 38, 43,
44, 45, 54, 57, 60, 62, 64, 67, 69, 71, 79, 82, 85, 86, 87, 95, 98, 100, 108,
111, 112, 113, 114, 115, 117, 118, 119, 120, 123, 127, 133, 142, 144, 145, 160,
161
Bacterial adherence, 11, 69, 79
Bacterial adhesion, 10, 11, 19
Bacterial adhesive, 11
Bacterial antigen, 32
Bacterial ATP, 144
Bacterial avoidance, 113
Bacterial biofilm, 10
Bacterial capsule, 25
Bacterial cell, 10, 11, 20, 34, 71, 117, 142, 144, 160, 161
Bacterial cell line, 11
Bacterial cell surface, 117, 144
Bacterial cell wall, 20, 34, 144
Bacterial charge, 144
Bacterial coat, 144
Bacterial colonization, 10
Bacterial cytoplasm, 144
Bacterial DNA, 82
Bacterial endosymbiont, 119
Bacterial endotoxin, 43, 113
Bacterial enzyme, 119
Bacterial exotoxin, 115, 120
Bacterial extracellular protein, 120
Bacterial factor, 115, 119
Bacterial flagellin, 22
Bacterial glycocalyx, 14
Bacterial growth, 10, 11, 34, 45, 57
Bacterial infection, 27, 31, 44, 45, 95, 100, 133, 161
Bacterial keratitis, 10
Bacterial meningitis, 25, 60, 86
Bacterial metabolism, 54, 112
Bacterial motility, 19
Bacterial multiplication, 119
Bacterial negative charge, 144
Bacterial neurotoxin, 118
Bacterial outer membrane(/coat), 27, 144
Bacterial overgrowth, 87
Bacterial pathogen, 23, 26, 34, 111, 114
Bacterial peritonitis, 127
Bacterial phagocytosis, 67
Bacterial product, 34
Bacterial proton gradient, 144
Bacterial ribosome, 123
Bacterial ssDNA, 82
Bacterial surface, 20, 25, 34, 114, 144, 145
Bacterial surface charge, 144, 145
Bacterial toxin inhibitor, 85
Bacterial viability, 10
Bacterial?resistant, 14
Bactericidal, 11, 20, 60, 70, 116, 160
Bacteriocrit, 158
Bacteriophage, 15, 114, 161
Bacterium, 8, 19, 27, 31, 32, 34, 35, 79, 112, 113, 114, 115, 119, 144, 160,
161
Bacteroides fragilis, 117
Bacteroides gingivalis, 25
Baier, R.E., 12
Baker, James R., Jr., preface, 29, 84
Ballooning, 152
Banana, 41
Barbario, J.R., 71
Barbiturate, 1, 13
Barker, Peter E., preface
Barnacles, 50
Barosensor, 137
Basal lamina, 78, 95, 106
Basal rate, 90, 147
Basement membrane, 87, 94, 105, 107, 108, 129
Basketball, 138
Basophil, 20, 24, 28, 36, 38, 40, 41, 66, 98, 113, 140
Bb, 23
BBB (blood brain barrier), 27, 43, 59, 60, 86, 87
B cell (B lymphocyte), 20, 21, 24, 25, 26, 28, 30, 31, 58, 88, 89, 106, 120,
141, 144
Becker, Wayne W., 27
Bedsore, 126
Beetle, 54
Beier, Rita, 106
Belladonna, 43
Bengal Civil Service, 2
Benjamini, Eli, 34
Benzene, 57
Benzoate, 112
Benzodiazepine, 13, 43
Benzyne, 58
Beryllium, 5, 120
BHK (cells), 18, 83
Bickerstaff, Linda, preface
Bile, 3, 42, 72, 125
Bilirubin, 103
Billroth’s cords, 95, 103
Binding affinity, 25, 41
Binding pad, 87
Binding site aperture, 146
Binding sites, 10, 13, 19, 21, 26, 27, 28, 29, 41, 59, 87, 112, 117, 119, 140,
146, 151
Bioacoustic, 11
Bioactive, 9, 10, 16, 41, 57, 59, 78, 79, 113
Bioactive materials, 9, 16
Bioadhesion, 19
Bioceram, 76, 77, 78, 79, 81
Biocompatibility of carbon fullerenes, 55
Biocompatibility of dendrimers, 84
Biocompatibility of diamond, 49, 52, 53
Biocompatibility of diamond particles, 49, 53
Biocompatibility of diamond?coated prostheses, 52
Biocompatibility of DNA, 81
Biocompatibility of fluorocarbon polymer, 68
Biocompatibility of metals, semiconductors, and quantum dots, 83
Biocompatibility of nanomedical materials, 49
Biocompatibility of nanorobot effluents and leachates, 88
Biocompatibility of nanorobot fragments, 93, 122
Biocompatibility of nondiamondoid carbon, 61
Biocompatibility of other nanomedical materials, 81
Biocompatibility of sapphire, ruby, and alumina, 75
Biocompatibility of shape memory materials, 83
Biocompatibility of Teflon particles, 72
Biocompatibility of Teflon?coated prostheses, 68, 71
Biocompatibility test methods, 11
Biocompatibility with neural cells, 85
Biodistribution, 59, 84, 85, 123
Biofeedback signals, 143
Biofilm, 10, 11, 19, 71, 87, 88, 111, 117
Biofilm bacteria, 11
Bioglass, 9
Biological adhesion, 145
BIOLOX, 77
Biomaterial, 7, 8, 10, 11, 12, 13, 15, 16, 24, 49, 52, 53, 79, 81, 85, 132
Biomimetic, 14, 15
BionitR, 76, 81
Biopore, 68
Bioresorbable, 9, 74
Biorobot, 81, 121, 123
Biosensor, 19, 52, 56, 61, 63, 64, 84
Biotechnology, 88, 122, 143, 149, 162
Bird toxicity, 73
Bishop, Forrest, preface
Black, Jonathan, 11, 12, 47, 99, 111
Blackthorn, 23
Blistering, 150
Block, Steven M., 152
Blockade, 36, 43, 66, 100, 103, 112, 121
Blood, 7, 8, 9, 10, 11, 12, 13, 14, 16, 17, 18, 20, 21, 22, 23, 24, 26, 27,
28, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 43, 44, 45, 46, 49, 51,
52, 54, 58, 59, 60, 61, 62, 63, 64, 66, 67, 69, 70, 71, 72, 73, 75, 76, 78,
79, 80, 81, 82, 83, 84, 86, 87, 89, 90, 93, 94, 95, 96, 97, 98, 99, 100, 101,
102, 103, 104, 105, 106, 107, 108, 111, 113, 114, 115, 121, 122, 123, 126, 128,
129, 130, 131, 132, 133, 135, 137, 138, 139, 140, 141, 142, 145, 146, 147, 152,
154, 155, 156, 157, 158, 159, 161
Blood aluminum, 81
Blood cell, 10, 18, 20, 21, 24, 31, 34, 35, 41, 62, 69, 72, 79, 94, 95, 96,
102, 103, 108, 137, 139, 140, 142, 147, 152, 157, 158, 159
Blood circulation, 93, 95, 96, 105, 108, 140
Blood clot, 12, 70, 83, 84, 133, 145
Blood coagulation, 35, 37, 62, 82
Blood compartment, 44, 66, 101, 146, 157, 158
Blood concentration, 39, 43, 44, 49, 72, 139
Blood contact test, 11, 12
Blood cyst, 70
Blood dialysis, 138, 147
Blood dust, 95
Blood elimination half?life, 100
Blood filtration, 17, 94
Blood flow, 24, 35, 36, 52, 62, 63, 70, 90, 93, 94, 97, 111, 126, 130, 133,
138, 158
Blood gas, 8
Blood group, 28, 31
Blood heat capacity, 89
Blood mucoprotein, 138
Blood perfusion, 94, 95, 97
Blood pH, 81
Blood plasma, 12, 26, 46, 86, 103
Blood plasma volume, 157
Blood pressure, 35, 40, 43, 128, 129, 157, 158
Blood protein, 13, 51, 75, 101, 102, 122
Blood pump, 9, 46, 52, 78
Blood serum, 75, 76, 82
Blood shear, 130
Blood sludging, 159
Blood supply, 33, 78, 108, 126
Blood thermal conductivity, 89
Blood transfusion, 30, 31, 138
Blood velocity, 133, 145
Blood vessel, 7, 13, 18, 20, 38, 40, 41, 44, 52, 64, 72, 86, 93, 94, 95, 97,
104, 106, 108, 123, 128, 129, 130, 131, 132, 133, 138, 140, 142, 155
Blood volume, 39, 40, 43, 73, 81, 89, 128, 157, 158
Blood?brain barrier (BBB), 27, 43, 59, 60, 86, 87
Blood?brain integrity, 156
Blood?contact material surfaces, 145
Blood?contacting surface, 9, 32, 38, 39, 52, 69, 132
Blood?exposed, 63
Blood?material interactions, 7
Blood?tissue barrier, 32
Bloodborne actin, 123
Bloodborne DNA?based nanodevice, 82
Bloodborne medical nanorobot, 49, 86
Bloodborne microparticle, 100
Bloodborne nanodevice surface, 145
Bloodborne nanorobot, 41, 96, 133, 141
Bloodborne particle, 94
Bloodletting, 128
Bloodstream, 9, 14, 15, 17, 20, 21, 26, 28, 33, 38, 39, 42, 43, 44, 46, 79,
81, 82, 84, 87, 88, 93, 97, 98, 99, 101, 106, 111, 114, 127, 132, 133, 135,
137, 138, 139, 140, 154, 155, 157, 158, 159
Bloodstream calcium, 9
Bloodstream clearance, 14
Bloodstream concentration, 44, 46, 81
Bloodstream half?lives, 14, 97
Bloodstream intrusiveness, 157, 159
Bloodstream?resident medical nanorobot, 42
B lymphocyte (B cell), 20, 21, 24, 25, 26, 28, 30, 31, 58, 88, 89, 106, 120,
141, 144
Bone cell, 8, 70, 78, 80, 136, 143
Bone marrow, 14, 20, 21, 30, 31, 67, 79, 94, 99, 101, 103, 105, 108, 121, 138
Bone morphogenetic protein (BMP), 111
Bone sialoprotein (BSP), 79
Boone, C.W., 47
Bordetella pertussis, 113, 115, 119
Borrelia recurrentis, 34, 35
Boutorine, A.S., 61
Bovine serum albumin, 14, 51, 61, 75, 76; see also BSA
Bowman’s capsule, 103
Brachiation, 97
Brachymetatarsy, 77
Bradbury, Robert J., preface, 39, 118, 122, 123, 131, 143, 161
Bradykinin, 35, 38, 40, 43, 86, 125
Brain, 27, 32, 33, 42, 43, 57, 59, 60, 73, 74, 85, 86, 87, 90, 93, 99, 101,
104, 105, 106, 123, 134, 137, 150, 156, 157, 159
Brain, Joseph, 55
Brain macrophage, 137
Brand, K.G., 47
Brass, 85
Breast milk, 26, 27
Brefeldin A, 147
Brodbeck, W.G., 145
Bronchoconstriction, 40, 127
Broncholithiasis, 45
Brooklyn College, 55
Brownian motion, 139
Brucella abortus, 25, 34, 119, 120
Bruising, 126, 127, 128
Brushite, 23, 53
BSA, 14, 51, 58, 75, 85, 103; see also bovine serum albumin
Bubble formation, 152
Bubblecrit, 158
Buckyball, 55, 57, 60, 61
Buckypaper, 56
Buckysome, 60
Buckytube, 55, 57
Buller, C., 104
Burden, 4, 67, 106, 107, 108, 109, 157, 160, 161
Burden of resident particle, 106
Bursting force, 141
Bursting strength, 141
Bushko, Renata G., preface
Butanedione monoxime, 117
C
C fiber, 125, 126
C Sixty, 60, 61
C1, 22, 23, 24, 36
C1 esterase inhibitor, 24
C1 INA, 24
C1 inactivator, 24
C1 INH, 24
C1 inhibitor, 36
C1?C9, 22
C1q, 23, 25, 63
C1r, 23, 24
C1s, 23, 24
C2, 20, 23, 24
C2a, 23, 25
C2b, 23, 24
C3, 20, 23, 24, 25, 31, 50, 159
C3 convertase, 23, 24, 25
C3 INA, 25
C3 nephritic factor, 23
C3?convertase, 23
C3a, 23, 24, 25, 40
C3b, 23, 24, 25, 102, 118
C3b INA accelerator, 25
C4, 23, 25
C4a, 20, 23, 24
C4b, 23, 24, 25
C4bp, 25
C5, 20, 23, 25
C5a, 23, 24, 25, 40, 71, 113
C5a peptidase, 113
C5b, 23
C5b67, 23, 24, 25
C5b678, 23
C5b6789, 23, 24
C6, 23, 25, 64
C60, 4, 28, 46, 55, 56, 57, 58, 59, 60, 61, 69, 89
C60 fulleropyrrolidone, 60
C60 monomalonate, 61
C60 trisamine, 61
C60?dimalonic acid, 61
C60?PEG, 59, 60
C60 (OH)24, 60
C62 bis(malonate), 61
C7, 23
C70, 28, 46, 56, 57, 58
C8, 23, 25
C82, 59
C9, 22, 23, 25
Ca, 23, 38, 39, 40, 50, 117, 118, 119, 130, 131, 136, 141, 147
Cachectin, 43
Cadherin, 119, 135
Calcification, 7, 9, 71, 72, 83, 108, 126, 135
Calcineurin, 30
Calciphylaxis, 126
Calcite, 29
Calcium, 9, 23, 29, 36, 45, 54, 70, 81, 107, 113, 118, 131, 136, 144, 153
Calcium oxalate, 29, 36, 45
Calcium phosphate, 9, 36, 41
Calcium pyrophosphate dihydrate (CPPD), 23, 36, 45, 54
Calculi, 109
Calmodulin, 61
Calor, 35
CaM kinase, 147
Camouflage, 14, 15, 29, 30, 31, 32, 146; see also immune system
cAMP, 115, 120, 131
Camptothecin, 86
Cancer, 5, 46, 47, 55, 56, 57, 60, 68, 85, 135, 149, 157
Candida, 34
“Candy wrapper” effect, 132
Canine, 18, 54, 69, 70, 71, 77, 94, 97, 127, 130, 132, 134, 135, 156
Cannabinoid, 113
Capacitance, 112, 121, 144
Capillaritis, 133
Capillary waves, 19
Capsule(s), 3, 9, 25, 61, 62, 63, 64, 70, 72, 76, 77, 78, 85, 95, 108, 110,
111, 114, 117, 122
Carasso, Barbara, preface
Carbohydrate, 14, 15, 22, 23, 24, 28, 29, 32, 88, 89, 143, 153
CarboMedics, 9
Carbon black, 5, 28, 36, 38, 41, 46, 56, 61, 65, 66, 67, 68, 86, 121, 123
Carbon dioxide, 88
Carbon disulfide, 58
Carbon fiber composite, 61, 64
Carbon fullerenes and nanotubes, 55, 58
Carbon monoxide, 4, 75
Carbon Nanotechnologies Inc., 55
Carbon nanotube, 13, 28, 36, 46, 55, 56, 57, 58, 59, 60, 61, 85, 144
Carbon particle, 4, 5, 28, 45, 53, 62, 63, 64, 65, 66, 67, 68, 99, 100, 101,
102, 103, 104, 107, 108, 111, 116, 121, 123, 156, 157, 158, 160
Carborundum, 5
Carboxyfullerene, 58, 59, 60, 61
Carboxylic acid, 9, 46, 56, 57, 58, 61
Carboxymethylcellulose, 139
Carboxypeptidase N (CPN), 25
Carcinogen, 46, 47, 57
Carcinogenesis, 46, 47
Carcinogenic, 2, 5, 7, 11, 46, 47, 53, 55, 56, 57, 73, 74, 78, 79
Carcinoma, 46, 60, 67, 97, 109
Cardiac arrest, 41, 135
Cardiac regurgitation, 97
Cardiff University, 19
Cardiomegaly, 156
Cardiomyocyte, 133
Cardiomyopathy, 151
Cardioplegic, 134
Cardiopulmonary bypass, 101
Carlton, Celeste, preface
Carotid, 73, 74, 87, 130, 133
Carr, K.E., 105
Carrageenan, 121
Cartilage, 32, 45, 63, 77, 78, 135, 136
Case Western Reserve University, 15
Cat, 42, 86, 97, 127, 140
Catabolism, 11
Catelas, Isabelle, 80
Catheter, 8, 10, 11, 17, 38, 42, 52, 63, 70, 71, 72, 78, 83, 93, 126, 132, 133,
134, 135, 138, 140
Catholic University in Leuven, 5
Cation, 131, 144
Cavalcanti, Adriano, preface
Caveolae, 117
Cavitation, 8, 11, 145, 152, 153
CB, 65, 66, 67, 68
CD100, 113
CD11b, 13, 63, 113, 118
CD18, 13, 113, 118, 136
CD2, 136
CD28, 31
CD3, 21, 31
CD31, 116
CD4, 21, 31, 59
CD40, 29
CD45, 136
CD47, 114
CD59, 25
CD61, 79
CD62, 63
CD62L, 136
CD8, 21, 31, 100
CD94, 20
CD95, 31, 32, 33
CD95L, 32, 33, 120
CDC42, 116
Cefotaxime, 113, 115
Cell, 5, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24,
25, 26, 28, 29, 30, 31, 32, 33, 34, 35, 36, 38, 39, 40, 41, 43, 44, 46, 47,
51, 52, 53, 54, 55, 57, 59, 60, 61, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72,
73, 74, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 93, 95, 96,
98, 99, 100, 102, 103, 104, 105, 107, 109, 111, 112, 113, 114, 115, 116, 117,
118, 119, 120, 121, 122, 123, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137,
138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153,
156, 157, 158, 159, 160, 161; see also cyto-
Cell adhesion, 7, 10, 13, 14, 16, 17, 51, 52, 54, 60, 71, 79, 85, 116, 119,
130, 132, 136, 142
Cell adhesion molecule, 116, 119, 130
Cell and tissue response to bulk Teflon, 69
Cell apoptosis, 15, 130, 131, 141
Cell attachment, 9, 13, 16, 17, 19, 51, 53, 71, 86
Cell burden, 160
Cell containerization, 142, 153
Cell cortex, 150
Cell culture, 11, 18, 60, 65, 80, 86, 89
Cell cycle, 7, 149
Cell damage rate (by nanorobots), 137
Cell desiccation, 143
Cell division, 30, 47, 118, 150
Cell enucleation, 118
Cell(ular) galvanotaxis, 144
Cell growth, 9, 13, 17, 51, 57, 60, 64, 85, 142
Cell junction, 128
Cell lysis, 22, 57, 141, 147, 161
Cell membrane, 10, 11, 14, 18, 20, 21, 22, 23, 24, 28, 44, 57, 84, 87, 123,
135, 136, 137, 138, 139, 140, 141, 143, 144, 146, 147, 150, 152
Cell membrane fluctuation, 137, 139, 140, 141
Cell metabolic activity, 7
Cell nucleus, 145, 152, 161
Cell proliferation, 7, 17, 31, 33, 66, 79, 83, 131, 144
Cell protein, 7, 55, 78
Cell receptor, 16, 21, 30, 31, 89
Cell reproduction, 11
Cell response to bulk alumina and sapphire, 78
Cell response to diamond surface, 51
Cell response to patterned surfaces, 17
Cell spreading, 16, 17, 18, 119, 142
Cell survival, 11
Cell vesicle budding, 144
Cell?binding, 14, 16, 17, 115
Cell?cell electrostatics, 144
Cell?cell recognition, 14
Cell?mediated immunity (CMI), 21, 41
Cell?nanorobot, 13, 143
Cell?polymer interface, 8
Cell?repulsive, 17, 85
CellCept, 30
Cellini, Benvenuto, 2
Cells, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22,
23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41,
43, 44, 45, 46, 47, 49, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63,
64, 65, 66, 67, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 82, 83, 84,
85, 86, 87, 88, 89, 94, 95, 96, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107,
108, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 125,
127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142,
143, 144, 146, 147, 148, 149, 150, 152, 153, 155, 156, 159, 160, 161, 162
Cells confinement, 142
Cellular defense, 4
Cellular dissociation, 11
Cellular intrusiveness, 159
Cellular volumetric burden, 160
Cellulitis, 127
Cellulose, 9, 25, 39, 100, 106, 134, 139, 145
Celsus, Cornelius, 35
CEM (cell), 59, 60
Center for Biologic Nanotechnology, 84
Center for Biological and Environmental Nanotechnology (CBEN), 55, 81
Centrosome, 150
Ceram alumina, 76
Ceramide, 60, 116
Cerebrospinal fluid, 8, 71, 86, 105, 156; see also CSF
Cereport, 86
Cervix, 24, 34, 60, 93, 104
Cetirizine, 41
CFRC, 64, 65
Chang Kai-Chien, 13
Chaotropic ions, 28
Charcoal, 53, 64, 65, 82
Charcot?Marie?Tooth disease, 150, 151
Charged bacteria, 144
Charged particle, 100, 145
Chattoraj, D.K., 75
Cheilitis, 107
Chelator, 136
Chemical inertness of diamond, 49, 54
Chemical inertness of Teflon, 68, 74
Chemical stability of alumina and sapphire, 75, 81
Chemical vapor deposition, 28, 36, 52
Chemisorption, 38, 68
Chemokine, 36, 110, 113, 115
Chemokinesis, 112, 113
Chemoreceptor trigger zone (CTZ), 43, 87
Chemorepellent, 87, 112, 113, 121
Chemorepulsion, 112, 114
Chemotactic, 24, 25, 40, 53, 58, 66, 80, 99, 101, 109, 110, 112, 113, 122
Chemotaxis, 11, 22, 59, 60, 99, 112, 113
Chen, Jian-Jun, 33
Chen, Li-Tsun, 96
Chicken, 66, 67, 101, 104, 106, 127, 136
Chigger, 127
Childbirth, 156
Chills, 41
Chilomonas paramecium, 112
Chimeric molecule, 25
Chlamydia pneumoniae, 34, 119
Chloramphenicol, 117
Chloride, 119, 137
Chlorine, 43
Chlorpheniramine maleate, 41
Chlorpromazine, 112
Choi, Stephen U.S., 90
Cholecystokinin, 115
Cholelithiasis, 45
Cholesterol, 29, 45, 93, 100, 109, 120, 139, 146, 160
Cholesterol crystal, 45, 160
Cholesterol monohydrate, 29
Cholinergic, 43, 61
Chomatin, 141
Chondrocalcinosis, 45
Chondrocyte, 17, 78, 135, 136, 144, 153, 160
Chondrogenesis, 57, 70
Chorioamnionitis, 104
Choroid plexus, 87
Christel, P.S., 80, 81
Chromium, 8, 41, 47, 52, 54, 63, 75
Chrysotile, 47
Chu, Benjamin, 9
Chylomicron, 95, 102, 141
CIA, 66
Cibacron blue, 112
Circle of Willis, 98
Cirrhotic, 94
Ckine, 22
Classical pathway, 22, 23, 24
Clathrin, 59, 117
Clearance of ingested particles, 105
Clearance of inhaled particles, 106
Clearance of particles from tissues, 104
Clements, Ken, preface
Clonal deletion, 29, 30, 33, 87
Clopidogrel, 40
Clostridium difficile, 116
Clostridium perfringens, 113, 117
Clottocyte, 39
Clowes, Alexander W., 132
Clubbing, 110
Clusterin, 25
CMF, 53, 139, 141
CNI?1493, 36, 115
CNS, 27, 35, 45, 85, 105, 112, 157
CO2, 8, 64, 88, 120, 156
Coaggregation, 142
Coagulase, 32, 114
Coagulation, 7, 12, 35, 37, 38, 39, 40, 43, 44, 49, 50, 62, 82, 138, 140, 145,
153, 159
Coagulopathies, 159
Coal, 4, 5, 107, 109
Coal dust, 5, 106, 107, 109
Coal fly ash particle, 107
Coarctation, 138
Cobalt, 5, 6, 8, 41, 47, 52, 54, 63, 80
Cobalt particle, 5, 80
Cobra venom factor, 23
Cokelet, G.R., 96
Colcemid, 118
Colchicine, 115, 118, 141
Cold shock, 143
Coles, L. Stephen, preface
Colitis, 43
Collagen, 8, 9, 10, 13, 16, 17, 35, 38, 45, 51, 64, 65, 67, 70, 71, 72, 74,
78, 79, 86, 105, 109, 110, 123, 137, 144, 155, 159, 160
Collagenase, 65
Collide, 111, 133, 141
Collision, 133, 134, 138, 139, 140, 141, 146, 154
Colloidal, 65, 66, 67, 86, 95, 102, 103, 104, 108, 109, 121, 138, 158
Colloidal carbon, 65, 66, 67, 86, 103, 104, 108, 109, 121, 158
Colominic acid, 32
Colon(ic), 3, 41, 42, 43, 66, 106, 126, 127
Colostrum, 27
Colwell, Rita R., 143
Commensal bacteria, 43
Communicyte, 110
Complement, 7, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 31, 32, 33, 34, 35,
37, 38, 40, 41, 43, 50, 54, 63, 71, 82, 85, 88, 89, 99, 101, 102, 113, 114,
115, 116, 119, 123, 125, 132, 145, 153
Complement activation, 7, 21, 22, 23, 24, 25, 27, 29, 32, 33, 43, 71, 85, 89,
145
Compliance, 133, 139, 143
Conceptus, 59
Concussive, 133, 134, 138
Condroitin, 23
Congenital brain malformation, 150
Congestive heart failure, 128
Connexin, 136
Conomos, Cynthia, preface
Contact dermatitis, 41, 125
Contact guidance, 18, 85, 110
Contusion, 44
Convoy, 87, 126, 129, 142
Copper, 42, 45, 72, 85, 90, 132
Copper particle, 90
Coppin, Chris M., 151
Cornea, 17, 32, 37, 72, 104, 128
Corpus callosum, 45
Corrosion, 8, 10, 52, 54, 61, 68, 81, 85, 93, 111, 144
Corticosteroid, 30, 33
Cortisone, 121
Corundum, 6, 75, 80
Cosmetic surgery, 74
Costochondral, 17, 78
Cotton, 109
Coumarin, 39
Countess of Essex, 1
Cr, 50, 66, 68, 77, 79, 115
CR1, 24
CR2, 24
CR3, 24
CR4, 24
Cranial, 43, 78, 83, 156, 157
Cranium, 12
CRE, 131
Creatinine, 97
Cretaceous?Tertiary boundary, 56
Cricothyroid, 73
Crinal, 126
Cristobalite, 107
Crooke, William, 2
Crosby, Carol Beck, preface
Crotalin, 40
Crush test, 127
Cryptococcus neoformans, 31
Cryptosporidium, 35
Crystal deposition, 36, 45, 103, 160
Crystal deposition disease, 36, 45, 160
Crystalite Corp., 2
Crystalloid bodies, 159
Crystalluria, 45, 104
CSF, 21, 45, 64, 69, 80, 105, 118, 156, 157; see also cerebrospinal fluid
CTZ, 43
Cultured cell, 16, 18
Curtis, Adam S.G., 10, 18
CVD (chemical vapor deposition), 28, 36, 49, 51, 52, 89
Cyanide, 1, 28
Cyanosis, 5, 40
Cyclic mechanical strain, 131
Cyclic mechanical stretch, 131
Cycloaddition, 13
Cyclodextrin, 56, 58
Cycloheximide, 118
Cyclopropane, 58
Cyclosporine, 30, 113
Cystic fibrosis (CF), 137, 147
Cytoambulation, 129, 130
Cytocarriage, 16, 20, 23, 35, 139, 148
Cytochalasin B, 115, 123, 141
Cytochalasin D, 115
Cytochrome, 15, 46, 59, 112, 148, 149, 153
Cytocide, 120, 128
Cytocompatibility, 57, 78, 80
Cytokeratin, 76
Cytokine, 20, 21, 22, 28, 31, 33, 35, 36, 43, 44, 45, 46, 53, 67, 69, 72, 82,
87, 99, 100, 109, 110, 111, 112, 131, 134, 160
Cytolysin, 120
Cytolysis, 23, 24, 120, 139, 140, 150
Cytomegalovirus, 121
Cytopenetration, 19, 33, 52, 87, 112, 118, 119, 136, 138, 153
Cytoplasm, 26, 34, 46, 53, 57, 76, 83, 86, 98, 100, 102, 104, 105, 114, 117,
118, 119, 122, 141, 142, 143, 144, 147, 148, 149, 150, 152, 153, 159, 161
Cytopuncture, 146, 147
Cytoskeleton, 18, 19, 51, 78, 87, 95, 116, 117, 135, 136, 137, 139, 147, 148,
149, 150, 151, 152, 153, 161
Cytoskeleton associated protein, 150
Cytosol, 21, 35, 44, 59, 82, 83, 84, 100, 116, 119, 120, 121, 139, 141, 147,
148, 149, 153, 159, 161
Cytosolic leakage, 147, 153
Cytosolic nuclease, 82, 149
Cytosolic protein, 21, 153
Cytotoxic(ity), 5, 12, 20, 21, 27, 30, 31, 33, 41, 47, 49, 51, 52, 55, 56, 57,
58, 60, 69, 75, 78, 80, 83, 84, 87, 89, 100, 109, 110, 112, 113, 115, 116, 118,
120, 122, 142, 144, 145, 160
D
Dacron, 17, 63, 70, 71, 132
DAF, 24, 25
Dalargin, 86
Damage rate (by nanorobots), 12, 137, 146
Damaged glycocalyx, 146
Damge, C., 105
DAMGO, 113, 115
Dansylcadaverine, 115, 120
Davis, S.S., 114
de Medici, Catherine, 2
De qi, 126
De?differentiation, 7
Deamer, David W., 27
Decompression nucleation, 145, 152
Decoys, 29, 34, 43, 84
Decubitus, 126
DeGennes P.G., 14
Degranulation, 39, 40, 53, 67, 99, 115, 118, 139, 141
Dehring, D.J., 101
Dehydration, 36, 43, 44, 143
Delayed?type hypersensitivity, 11, 30, 32, 41, 125
DTH, 30, 41
Democritus, quotes
Denaturation, 28, 44, 49, 50, 51, 62, 69, 76
Dendrimer, 49, 81, 84, 85, 153
Dendrite, 148
Dendritic cells (DCs), 21, 22, 24, 31, 33, 100, 131, 137
Dental, 3, 5, 8, 9, 10, 36, 52, 62, 63, 70, 75, 76, 77, 78, 122, 134
Denudation, 133, 134
Deoxynucleoside, 82
Deoxyribonucleic acid, see DNA
Dephosphorylation, 116
DePTFE, 68, 70
Derivatized carbon fullerenes and nanotubes, 58
Dermatitis, 5, 40, 41, 125, 126
Dermis, 22, 64, 105, 107, 110, 127, 155
Desialylated glycocalyx, 145
Desiccation, 142, 143
Detachment, 12, 14, 15, 29, 67, 72, 104, 116, 134, 135, 145, 151, 152, 153
Dexamethasone, 103, 115, 120, 132
Dextran, 15, 23, 86, 97, 101, 103, 114, 121, 127, 139
d’Herelle, 114
Diabetes, 150, 159
Diabetic, 51, 104, 139
Diacylglycerol, 131
Dialysis, 81, 85, 126, 138, 147, 156, 157
Dialyzer, 7
Diamond, 1, 2, 3, 4, 5, 6, 8, 9, 11, 13, 15, 19, 23, 24, 28, 29, 36, 38, 41,
45, 46, 49, 50, 51, 52, 53, 54, 61, 64, 68, 69, 75, 85, 87, 88, 89, 90, 91,
99, 100, 101, 105, 106, 108, 109, 122, 126, 132, 138, 142, 154, 155, 156, 160
Diamond crystal, 49, 53, 54, 99, 156
Diamond dust, 1, 2, 4, 5, 6, 53, 54, 108, 109, 160
Diamond dust particle, 54, 160
Diamond grit, 2, 126
Diamond grit particle, 126
Diamond particle, 1, 2, 4, 6, 15, 23, 36, 49, 53, 54, 89, 99, 100, 105, 109,
155, 156, 160
Diamond?coated, 8, 38, 49, 52, 54, 132
Diamondoid, 1, 4, 6, 10, 16, 20, 28, 29, 36, 38, 41, 47, 49, 50, 51, 52, 53,
54, 61, 68, 81, 87, 88, 89, 90, 99, 102, 107, 109, 110, 121, 122, 126, 139,
143, 148, 151, 154
Diamondoid particle, 89, 109
Diapedesis, 96, 104, 128, 141, 142, 144
Diarrhea, 3, 126, 127, 128
Diastole, 129
Diathermy, 90
DIC, see disseminated intravascular coagulation
Dichlorobenzene, 58
Dichloromethylene diphosphonate, 120
Diclofenac sodium, 36, 113
Dictyostelium discoideum, 153
Differential gear, 122
Differentiation, 7, 17, 21, 22, 33, 47, 57, 59, 66, 71, 79, 80, 99, 101, 114,
122, 130, 131, 132, 136, 149
Diffusion through granuloma, 110
Dilantin, 13, 45
Dimalonic acid C60, 59
Dimer placement mechanosynthesis tool tip, 122
Dimethyldioctadecylammonium bromide, 119
Diminazenediaceturate, 86
1,4?dinitrobenzene, 28, 29
Dion, I., 51, 54, 80
Dirofilaria, 135
Disaggregation, 139, 142, 144
Dissociated cell, 11, 17
Di Silvestre, M., 79
Disse space, 66, 95, 102
Disseminated intravascular coagulation (DIC), 44, 138, 140
Diverticulum, 74
DLC, 13, 36, 38, 46, 51, 52, 53, 54, 89, 132
DMSO, 112
DNA, preface, 30, 34, 46, 49, 55, 57, 59, 61, 62, 76, 78, 81, 82, 83, 84, 85,
87, 106, 123, 131, 144, 145, 149, 153
B?DNA, 82
cDNA, 31, 83
ssDNA, 82
dsDNA, 82, 83
z?DNA, 82
Dog, 3, 39, 61, 62, 63, 71, 72, 73, 74, 78, 80, 94, 97, 104, 107, 110, 111,
127, 132, 158
Dolor, 35
Donaldson, K., 123
Donaldson, P.E.K., 145
Dopamine, 43, 85
Dopaminergic, 45, 58
Doxorubicin, 86
DPA, 77
Drake, R.F., 17
Drexler, K. Eric, preface, 88, 122, 146, 148, 154
Drosophila, 57
Drukker, M., 33
Dubertret, Benoit, 84
Dugan, L.L., 61
Duncan, Alexander, 37
Duodenal, 42, 106, 127, 146
DuPont, 56
Dura mater, 71
Dural tear, 156
Durante of Brescia, 2
Durasphere, 68
Dust cell, 6, 99
Dust mite, 4, 40, 125
Dust particle, 54, 65, 98, 106, 108, 109, 160
Dutton, R.C., 12
Dye, William L., preface
Dynamin, 117, 118
Dynamin?binding site, 117
Dynein, 151
Dysenteric, 43
Dysesthesia, 150
Dysopsonic, 101
Dysphonia, 73
Dyspnea, 158
Dystrophic, 83, 147, 152
Dystrophic muscle cells, 147
E
EAG, 150
Eastman, J.A., 90
Ebola, 128
EC, 129, 130, 131, 132
Ecchymosis, 128
Eclampsia, 138
ECM, 16, 17, 18, 86, 123, 135, 136, 137, 142, 149, 150, 153, 155; see also extracellular
matrix
Eczema, 40
EDDF, 118
Edema, 5, 35, 36, 40, 54, 66, 67, 79, 104, 115, 120, 127, 128, 129, 130, 133,
134, 137, 155, 157
Edentulous, 76
Effluents, 43, 47, 49, 86, 88, 89
EGTA, 39, 113
Ehrlichia (Cytoecetes), 119
Eicosapentaenoic acid, 113, 115
eIF4E?binding protein, 142
El Tor, 143
Elastase, 25, 40
Elasticity, 63, 133, 139, 141, 155, 157, 159, 161
Elastin, 155
Eldridge, J.H., 105
Electret, 39
Electric field?induced cell migration, 144
Electrical interactions with cells, 143
Electrocautery, 144
Electrochemical potential, 145
Electrocompatibility, 85, 125, 143, 145
Electrocution, 144
Electrolyte, 23, 158
Electron affinity, 50, 51, 57
Electronegativity, 50, 51
Electrophoresis, 144
Electroporation, 144, 147
Electrostatic contact potential force, 145
Electrostatic image force, 145
Electrotaxis, 144
Elephantiasis, 129
ELISA, 58
Elliptocytosis, 138, 150
Embolism, 9, 82, 83, 97, 135
Embolus, 8, 44, 45, 71, 93, 94, 97, 132, 134, 145
Embryo, 33, 46, 51, 57, 59, 71, 78, 84, 135, 147
Embryogenesis, 59
Emerson, Ralph Waldo, quotes
Emesis, 42, 43, 125, 126
Emetogenic(-esis), 42, 126
Emiling, Robert C., 22, 37
Emperipolesis, 161
Emphysema, 5
Emulsion particle, 118
Encapsulated bacteria, 95
Encapsulation, 7, 17, 58, 64, 70, 74, 77, 85, 110, 111
Encephalitis, 45, 86
Encephalomyelitis, 86
Endarterectomy, 133
Endocarditis, 9, 11
Endocardium, 134
Endocytic, 24, 35, 86, 104, 117, 118, 123
Endocytic index, 104
Endocytosis(-tic), 22, 59, 67, 82, 84, 100, 102, 115, 117, 118, 147, 149
Endometrium, 133
Endomorphine, 113, 115
Endoplasmic reticulum (ER), 26, 35, 78, 118, 119, 128, 146, 148
Endoprosthesis, 28, 63, 64, 72, 80
Endoscopic, 41, 66, 74
Endoscopic colonic tattooing, 41, 66
Endosome, 117
Endosteal, 62
Endosymbiont, 161
Endosymbiotic bacteria, 161
Endothelial(-ium), 5, 17, 18, 31, 32, 35, 36, 38, 39, 45, 51, 52, 59, 63, 66,
71, 85, 86, 94, 95, 96, 97, 98, 101, 102, 103, 107, 108, 114, 116, 121, 127,
128, 129, 130, 131, 132, 133, 134, 135, 140, 141, 142, 143, 144, 145, 146, 147,
150
Endothelial adhesion, 71, 141
Endothelial massage, 95
Endothelial phenotype and function, modulation of, 129, 130
Endothelial precursor stem cells, 132
Endothelial slit, 96
Endothelial tight junction, 142
Endothelialization, 38, 64, 71, 132, 135
Endotoxin, 15, 36, 43, 44, 45, 113
Engineered cell, 85
Engoren, 45
Enkephalin, 86
Enophthalmos, 72
Entactin, 16
Entamoeba histolytica, 25
Enterococci, 117, 120
Enterocyte, 146
Enterotoxin, 45
Enucleation, 118
Envasculoided, 90, 91
Enveloped virus, 16, 60, 114
Enzyme, 5, 8, 13, 23, 24, 25, 33, 34, 38, 40, 41, 46, 47, 51, 53, 54, 56, 58,
61, 65, 67, 68, 69, 73, 76, 78, 80, 82, 87, 88, 95, 100, 102, 111, 112, 115,
117, 119, 120, 121, 123, 125, 127, 131, 140, 141, 144, 145, 148, 149, 153
Enzyme complexes, 144
Eosinophil, 20, 23, 27, 28, 40, 66, 98, 99, 103, 107, 109, 118, 123, 159
EPA (Environmental Protection Agency), 4, 55
Epidermal, 9, 46, 57, 60, 64, 125, 126, 127, 131, 137, 144, 150
Epidermalgia, 125, 126
Epidermis, 9, 10, 14, 22, 57, 125, 127, 147
Epidural, 156
Epilepsy, 43, 86
Epileptogenesis, 86
Epimysial, 111
Epinastine, 41
Epinephrine, 41, 139
Episclera, 72
Epithelial(-ium), 3, 4, 5, 17, 18, 22, 24, 30, 33, 34, 40, 42, 46, 60, 63, 64,
67, 68, 71, 72, 73, 76, 78, 79, 98, 104, 105, 106, 107, 111, 117, 120, 122,
125, 126, 127, 128, 133, 137, 142, 144, 146, 147, 149, 150, 159, 160, 161
Epithelial pressure ulcers, 126, 133
Epitope, 13, 26, 28, 29, 30, 31, 32, 88
Epoxylite, 85
e?PTFE, 68, 70, 72
Eriksson, C., 63
Erlanger, B.F., 11, 59
Erythema, 35, 36, 82
Erythroblastosis fetalis, 41
Erythrocyte, 12, 15, 23, 24, 25, 29, 31, 33, 35, 44, 60, 62, 72, 74, 82, 85,
94, 95, 96, 97, 98, 99, 102, 103, 108, 114, 120, 121, 123, 125, 128, 132, 134,
135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 146, 147, 150, 152, 153, 157,
158, 159, 161
Erythrocyte aggregation, 137, 139
Erythrocyte surface fluctuations and elasticity, 139
Erythrocyte trauma, 138
Erythromelalgia, 125
Erythromycin, 115
Erythropathies, 138
Erythropoietic, 101
Erythropoietin, 138
ESCA, 58
Escalator, 106, 107
Escherichia coli, 11, 15, 19, 22, 32, 34, 43, 57, 60, 112, 117, 119, 161
Esophageal, 3, 42, 45, 68, 74, 126, 127, 137
Esophagus, 52, 127
eSpin Technologies, 9
Esthesiometer, 137
18?beta?estradiol, 131
ET?1, 130
Etanercept, 46
Ethanol, 58, 94, 115, 150
Ethmoidal, 42
Etoposide, 118
Euglena gracilis, 112
Eukaryotic cell, 14, 15, 46, 57, 120, 144, 160
Euler buckling, 150
Euvolemic, 128
Excited state, 56
Exocrine, 94, 118
Exocytic, 24, 116, 118
Exocytosis, 87, 98, 112, 116, 118, 119, 147
Exoprostheses, 126
Exotoxin, 115, 120
Exsanguination, 61, 158
Extracellular matrix, 13, 16, 17, 19, 72, 85, 125, 133, 135, 137, 155; see also
ECM
Extravasation, 73, 85, 101, 128, 142
Extrinsic pathway, 38, 39, 40
Extropy Institute, 14
Extrusion, 62, 72, 73, 111, 118
of cell nucleus, 118
of implant, 72, 111
Eye, 2, 5, 32, 33, 42, 44, 62, 66, 67, 72, 93, 94, 104, 105, 115, 156
F
Fab, 23, 26, 32, 59
Fabrey’s disease, 159
Factor B, 23, 24, 25
Factor D, 23, 25
Factor H, 24, 25
Factor III, 38
Factor IX, 38
Factor IXa, 38
Factor P, 23
Factor V, 38, 39
Factor Va, 38
Factor VII, 38
Factor VIII, 76
Factor X, 38, 39
Factor Xa, 38, 39, 40
Factor Xa inhibitor FX?2212, 39
Factor XI, 38
Factor XIa, 24, 38
Factor XII, 35, 36, 38
Factor XIIa, 24, 40
Factor XIIa inhibitor, 40
Factor XIIIa, 38
Fahy, Gregory M., preface, 8, 14, 143, 145
Failure strength, 63, 151, 154, 155
Falk, R., 106
Fardeau?Engel bodies, 160
Farnese, Pierluigi, 2
Fas, 32, 60
FasL, 32, 33
FC4S, 58, 59
FDA (Food and Drug Administration), 71, 73, 162
Fecal incontinence, 74
Feces, 43, 59, 123, 126
Feline, 97, 127
Fenart, L., 86
FEP, 141
Ferrofluid, 147
Ferrofluid particle, 147
Fetotoxicity, 46, 57
Fetus, 32, 138, 156
Fever, 7, 34, 36, 40, 41, 44, 45, 46, 66, 73, 74, 128, 161
Fewster, Stephen, 13
FGF, 131, 134
Fiberglass, 5, 125
Fibrin, 12, 13, 32, 37, 38, 39, 40, 50, 62, 63, 69, 79, 114, 135, 138, 139,
140
Fibrinogen, 10, 12, 13, 19, 32, 37, 38, 39, 49, 50, 61, 62, 63, 67, 69, 75,
102, 136, 139, 140
Fibrinolytic enzyme, 13
Fibroblast, 7, 10, 16, 17, 18, 29, 32, 33, 36, 46, 47, 51, 52, 54, 57, 62, 64,
65, 66, 67, 70, 72, 78, 80, 83, 98, 99, 101, 104, 105, 106, 110, 114, 120, 121,
122, 123, 127, 134, 136, 137, 141, 142, 143, 144, 146, 147, 149, 159, 160
Fibroid, 157
Fibromyalgia, 128
Fibronectin, 10, 13, 14, 16, 18, 32, 50, 69, 70, 71, 75, 86, 114, 123, 160
Fibroplasia, 110
Fibrosarcoma, 17, 60, 71
Fibrosis, 4, 5, 6, 7, 18, 49, 65, 67, 71, 73, 74, 77, 79, 80, 108, 109, 110,
129, 137, 147, 160
Fibrous particle, 5
Fields, Lars Lawrence, preface
Film Oasis, 14
Filovirus, 128
FimH, 19
Fine, Arthur, preface
Fine motion controller, 122
Fiorito, Silvana, 55, 57
Fish bone, 109
Fistula, 98, 130, 134, 138
Flagella, 34, 35, 112, 161
Flagellate bacterium, 112
Flitman, Steven S., preface, 13, 23, 27, 45, 46, 54
Fluid shear stress, 129, 130, 136, 140, 141
Fluorescence, 56, 59, 63, 78
Fluorescent particle, 100
Fluorinated ethylene propylene, 71
Fluorocarbon, 45, 50, 68, 69, 70, 72, 73, 74, 75, 85, 86, 89, 107
Fluorocarbon polymer, 68, 86
Fluoropassivated, 68
Fluoropeptide, 16
Fluorophore, 159
Fluoropolymer, 72
Fluorouracil, 85
Fluosol, 72
FMLP, 113, 118, 159
Foam cells, 159, 160
Focal adhesion, 135, 136
Follistatin, 82
Fonseca, Tim, preface
Food allergy, 40
Food poisoning, 21
Force threshold for biological response, 135, 136
Forced sieving, 95
Foreign body giant cell (FBGC), 65, 66, 70, 71, 72, 77, 78, 99, 102, 103, 109,
110
Foreign body granulomatous reaction, 74, 109, 134
Foreign body reaction, 7, 36, 62, 64, 65, 73, 74, 77, 98, 109, 110, 133
Foreign particle, 36, 47, 98, 99, 104, 107, 109, 116, 117, 121, 158, 160
Foreign?body carcinoma, 109
Foresight Institute, preface
Formed blood elements, 97, 145
Forrest, David R., preface
Fragmentation syndrome, 138
France, Richard, 9
Frankfurter Allgemeine Zeitung, preface
Frederick II, 1
Free radical, 40, 61, 79, 88, 98, 122, 134
Freitas, Barbara Lee, preface
Freitas, Nancy Ann, preface
Freitas, Robert A. Jr., preface, 3, 122
Freitas, Robert A. Sr., preface
Freund (bacterial adjuvant), 100
Frialit, 76
Friedman, David, preface
Fructosyl chondroitin, 32
Frustrated phagocytosis, 100, 112
Fujita, H., 102
Fujita, Tsuneo, 96
Fullerene, 23, 28, 36, 38, 41, 45, 46, 49, 55, 56, 57, 58, 59, 60, 61, 69, 85,
89, 153
Fullerene?based pharmaceuticals, 60, 153
Fullerenol, 58, 59, 60, 61
Fullereyl protein, 58
Fullerol, 46, 58, 59
Fungus, 31, 54, 58, 83, 147, 150
FUO, 45
Fusion protein, 19
Fusogen, 116, 119
G
G protein, 70, 117
Gabriel, Kaigham, 4
Gadolinium (Gd), 130
Gallbladder, 95
Gallstone, 45, 109
Galvanic, 61, 68
Galvanotaxis, 144
Gamma globulin, 30, 113
Ganglioside, 145
Gastric fundus, 146
Gastrin, 113, 115
Gastrointestinal, 3, 4, 27, 34, 42, 44, 82, 93, 105, 123, 127, 150
Gastrointestinal strangulation, 44
Gaucher’s disease, 156, 159
GdCl3, 116, 120, 121, 131
Gebert, Andreas, 106
Gelatin, 3, 66, 70, 71, 75, 100, 134
Gelsolin, 123
Gene therapy, 84, 122
Genistein, 115
Gennart, J. Ph., 6
Genomic cassette, 121
Genotoxicity, 5, 46, 47, 57, 67, 116, 122
Genotoxin, 115
Gentamicin, 11, 115, 149
Genzer, J., 16
Genzyme Corp., 9
Geometrical filtration, 94, 97, 101
Geometrical trapping elsewhere in the circulation, 97
Geometrical trapping in kidney, 97
Geometrical trapping in liver, 94
Geometrical trapping in liver vasculature, 94
Geometrical trapping in lung vasculature, 94
Geometrical trapping in spleen vasculature, 95
Geometrical trapping of bloodborne medical nanorobots, 93
Germanium, 5
Ghost red cells, 15, 98
Giant cell, 7, 16, 54, 63, 65, 66, 67, 70, 71, 72, 73, 74, 77, 78, 83, 99, 100,
102, 103, 105, 109
Gingiva, 33, 62, 76, 78, 80, 127
Gingivalis, 22, 25, 79
Glass, 2, 3, 5, 9, 10, 11, 15, 17, 18, 35, 37, 39, 41, 51, 64, 69, 70, 85, 90,
94, 106, 109, 134, 139, 140, 141, 143, 144, 150, 152
Glass particle, 37
Glassy carbon, 61, 62, 63, 85
Glaucoma, 72, 156
Glaumann, H., 123
Glial cell, 67, 85, 104, 105, 123
Gliosis, 67, 86
Glomerulonephritis, 103
Glomerulus, 67, 97, 103, 138
Glucan, 123
Glucocorticoid, 46, 120
Glucose, 15, 16, 51, 61, 88, 89, 112, 119, 120, 123, 129, 132, 145
Glucose tolerance test, 129
Glucosyl, 146
Glugea, 119
Glutaraldehyde, 139
Glutathione, 24, 58, 59, 68
Glycocalyx, 10, 13, 14, 15, 101, 102, 137, 145, 146
Glycocalyx damage, 146
Glycolipid, 14, 16, 119, 136
Glycophorin, 136
Glycophosphatidyl LFA?3, 136
Glycoprotein, 10, 14, 16, 17, 21, 24, 25, 26, 34, 41, 49, 75, 79, 103, 116,
119, 136, 145, 146
Glycoprotein C (gC), 25
Glycoprotein III (gIII), 25
Glycosaminoglycan, 38
Glycoside, 1, 15
Glycosylate, 14
Glycosylation, 123
GM?CSF, 21, 64, 80, 118; see also granulocyte?macrophage colony stimulating
factor
Gold, 14, 18, 19, 24, 29, 39, 41, 61, 62, 63, 68, 72, 83, 85, 87, 100, 101,
103, 132
Gold particle, 87, 101, 103
Gold?binding protein (GBP), 29
Golgi, 26, 78, 146, 147, 148
Gonzalez, Kelly A., 59
Goodpasture’s syndrome, 41
Gore?Tex, 11, 68, 70, 72
Gout, 36, 45, 46, 156
GpIIb?IIIa, 136
GR, 58
Graft, 7, 9, 10, 13, 15, 16, 17, 29, 30, 31, 32, 33, 38, 58, 64, 65, 68, 69,
70, 71, 72, 84, 121, 122, 130, 133
Gram?negative, 25, 43, 44, 112, 144
Gram?negative bacteria, 25, 43, 44, 144
Gram?positive, 44, 60, 64, 120, 144
Gram?positive bacteria, 44, 60, 144
Gramicidin A, 148
Granule, 23, 28, 38, 40, 82, 96, 98, 101, 118, 119, 141, 147, 151, 159, 160
Granulocyte, 21, 63, 64, 70, 95, 98, 103, 111, 113, 115, 118, 121, 140, 141,
144
Granulocyte?macrophage colony stimulating factor, 21, 64, 113, 118; see also
GM-CSF
Granuloma, 7, 45, 47, 56, 63, 64, 66, 67, 70, 71, 72, 74, 79, 83, 93, 94, 100,
102, 103, 107, 109, 110, 111, 112, 121, 122, 127, 129, 134
Granulomatogenesis, 101, 103
Granulomatous (reaction), 45, 47, 66, 70, 71, 74, 79, 109, 110, 111, 112, 122,
127, 134
Granulopoiesis, 121
Granulopoietic, 101
Graphene, 36, 46, 55, 57, 58, 60, 88, 89
Graphite, 5, 8, 14, 15, 23, 28, 36, 38, 41, 45, 46, 51, 54, 55, 61, 62, 63,
64, 68, 75, 88, 89, 109, 138, 152
Graphitic acid, 64
Graphitosis, 5, 63
Graphon surface, 64
Green, Katharine, preface
Griscelli syndrome, 151
Gristina, Anthony G., 10
Growing bacteria, 44
Grune & Stratton, Inc., 96
GSH, 58, 68
GST, 58
GTP, 112, 116, 142
GTPase, 115, 116, 117, 118
Guanine, 57, 61
Guanylhydrazone, 36
Guinea pig, 6, 55, 57, 59, 61, 62, 65, 68, 70, 77, 99, 107, 108, 109, 160, 161
Gulf General Atomic, 62
Guyton, Arthur C., 129
H
H9 (cell), 60
HA, 53
Hab, 31
Haberzettl, Cecilia, preface, 33
Haemophilus influenzae, 25, 34, 95, 114, 117
Hageman factor, 24, 35, 36, 38, 43
Hair follicle, 32, 125, 126, 127, 137
Halas, Naomi J., 84
Hall, J. Storrs, preface
Hallervorden?Spatz disease, 159
Halperin, James L., preface
Hamaker constant, 144
Hamill, Owen P., preface, 137, 143, 147, 148
Hamster, 4, 6, 18, 66, 71, 78, 109, 115
Hansen, J.O., 50
Haptic, 126
Haptoglobin, 138
Haptotaxis, 18
Hard metal lung disease, 5
Harfenist, Elizabeth J., 26, 27
Harms, J., 80
Harrison, R.G., 18
Harvard Department of Environmental Health, 55
Haubold, A.D., 68
Hay fever, 40
HBEGF (heparin binding epidermal growth factor), 131
HCME, 134
Hct, see hematocrit
HDP, 80
Headache, 41, 128, 156
Heart valve, 7, 8, 9, 10, 11, 38, 52, 62, 63, 75, 97, 114, 138
Heart valve biomaterials, 8
Heartworm, 135
Heat capacity, 75, 89, 90, 91
Heat shock protein (HSP), 35, 153
Hedenborg, Mikael, 6, 53
Heinz bodies, 95, 96
HeLa, 11, 60
Helbing, G., 63, 65
Helicobacter pylori, 25, 29, 32
HEMA, 14, 18, 85, 101, 139; see also hydroxyethylmethacrylate
Hematocele, 70
Hematocrit (Hct), 96, 128, 157, 158, 159
Hematoma, 128, 134, 157
Hematopoietic, 51, 71, 137
Hemidesmosome, 76, 78
Hemocompatibility, 51, 69
Hemoconia, 95
Hemodialysis, 13, 82, 140
Hemodilution limit, 158
Hemodynamic load, 147
Hemoglobin, 15, 75, 96, 103, 138
Hemoglobinuria, 138
Hemolysin, 118, 119, 120
Hemolysis, 7, 12, 38, 54, 64, 78, 80, 84, 135, 137, 138, 139, 140
Hemolytic?uremic syndrome, 138
Hemophilia, 70
Hemorrhage, 43, 66, 97, 127, 128, 133, 134, 157
Hemorrhagic fever, 128
Hemostasis, 39
HEP?2 (cell), 60
Heparin, 13, 23, 25, 36, 38, 39, 52, 89, 114, 131
Hepatocarcinogenic, 46, 72
Hepatocyte, 17, 18, 60, 66, 71, 95, 102, 117, 120, 121, 132
Hepatocyte growth factor, 132
Hepatoma cell, 60
Hepatomegaly, 156
Hepatosplenomegaly, 121
Herbimycin, 115, 130
Herelle, see d’Herelle
Hernia, 44, 72
Hewitt, John, preface
Hexa(sulphobutyl)fullerene, 61
Hexafluoroethane, 70
HIE, 113
Higson, F.K., 53
Hipper, A., 131
Hippocampal, 85
Hirano bodies, 159
Hirudin, 39
Histamine, 20, 22, 24, 28, 35, 36, 40, 41, 42, 43, 112, 125
Histiocyte, 72, 74, 99, 108
Histiocytoma, 47
Histiocytosis, 110
Histonatation, 86, 87, 135, 136, 137, 141
Histonatation, threshold for perceptible, 137
Histopenetration, 127, 128, 129
Histoplasma capsulatum, 34
HITT, 39
HIV, 54, 59, 60, 86
Hives, 40
Hixon, Hugh, preface
HLA, 20, 29, 30, 32, 33, 66
HMG, 36
Hogg, Tad, preface
Hoh, Jan H., preface
Holland, Nolan B., 15
Holy Roman Empire, 1
Homologous restriction factor (HRF), 25
Homotypic aggregation, 141
Hook, C. Christopher, preface, 84
Hormone, 40, 44, 95, 112, 115, 138
Host response, 7, 11, 12, 111
Houghton, Sue, preface
hPGT, 130
HPMA, 85
HRF (homologous restriction factor), 25
HRP (horseradish peroxidase), 116
HSA (human serum albumin), 12, 14, 51, 62
Hsp60, 35
Hsp70, 153
Hsu, Long, 151
HSV (herpesvirus), 25, 32, 86
5?HT, 36, 43
Huczko, Andrzej, 55
Hughes, Robert G., preface
Human blood, 21, 22, 23, 24, 40, 44, 51, 52, 62, 69, 70, 75, 80, 81, 82, 93,
99, 111, 115, 121, 133, 138, 139, 140, 141, 155, 157, 158
Humanize, 88
Hutchkinson, Maxwell, 1
Hyaline, 79
Hyalocyte, 66, 104
Hyaluronan, 9, 29, 54
Hyaluronic acid, 32, 33, 114
Hybridoma, 141, 152, 159
Hydrocarbon, 9, 29, 41, 45, 50, 51, 57, 58, 61, 62, 66, 73, 74, 79, 89, 122,
148
Hydrocarbon bearing, 122
Hydrocarbon universal joint, 122
Hydrocephalus, 8, 157
Hydrogen peroxide, 61, 67, 82, 98
Hydrophilic, 12, 13, 14, 15, 17, 18, 19, 23, 28, 39, 49, 50, 59, 63, 75, 76,
83, 94, 100, 101, 114, 116, 144, 145, 148
Hydrophobic, 10, 11, 12, 14, 15, 16, 17, 18, 19, 23, 28, 29, 49, 50, 52, 57,
58, 59, 62, 68, 69, 71, 72, 75, 76, 79, 81, 100, 101, 103, 117, 144, 148, 159
Hydroxyapatite, 9, 23, 28, 36, 41, 53, 54, 59, 78, 79, 80, 83, 100
Hydroxyethyl starch, 158
Hydroxyethylmethacrylate, 14; see also HEMA
Hydroxymethylation, 104
Hyperalgesia, 35, 126, 127
Hyperbaric, 128
Hypercapnia, 156
Hyperesthesia, 126
Hyperhidrosis, 45
Hyperimmunoglobulin?E, 113
Hyperion Catalysis International, 55
Hyperopia, 156
Hyperplasia, 67, 130, 132, 133, 134
Hyperplastic, 47, 107
Hypersensitivity, 7, 11, 20, 30, 32, 36, 40, 41, 125
Hypertension, 87, 94, 130, 133, 147
Hyperthermia, 44, 45, 87
Hypertrophy, 142
Hypervariable (regions), 26
Hyperventilation, 156
Hyperviscosity, 158
Hypervitaminosis A, 149
Hypha, 69, 150
Hypocapnia, 156
Hypochlorite, 112
Hypoglucosify, 119
Hypokalemia, 158
Hyponatremia, 158
Hypotension, 35, 40, 41, 97, 128, 129, 156, 158
Hypothalamus, 44, 45
Hypothyroid, 159
Hypotony, 72
Hypovolemic, 128
Hypoxia, 43, 119, 132
Hysteresis, 133
I
IAP, see inhibitor of apoptosis
IBD, 45
Ibuprofen, 39, 46
ICAM, 71, 86, 134, 136
ICD, 93, 134
Idarubicin, 86
Idiotype, 29
IFN, 21, 66, 103
IgA, 21, 23, 27, 28, 34, 40, 75, 118
IgD, 21, 28
IgE, 20, 21, 23, 28, 40, 41, 66, 73, 125
IgG, 21, 23, 24, 26, 27, 28, 33, 34, 41, 50, 58, 66, 69, 71, 73, 75, 82, 95,
99, 100, 102, 115, 116, 117, 160
IgM, 21, 23, 27, 28, 29, 41, 75, 116, 120
IIR, 66
IJE, 78
IL?, 16, 20, 31, 33, 44, 45, 46, 64, 69, 80, 82, 103, 110, 113, 118, 134; see
also interleukin
IL?1, 16, 44, 45, 46, 69, 82, 110, 118, 134
IL?2, 16, 31
IL?3, 118
IL?4, 20, 45, 103
IL?5, 118
IL?6, 20, 44, 45, 46, 80, 118
IL?8, 45, 64, 69, 113
IL?10, 31, 33, 46
IL?13, 20
Ileum, 42, 57, 59, 105, 106, 127, 146
Illum, L., 114
Imidazole, 112
Immune cell, 8, 20, 28, 31, 32, 33, 45, 83
Immune evasion, 20, 29, 33, 34, 35
Immune privilege, 20, 32, 33, 120
Immune system, 8, 11, 16, 20, 21, 22, 25, 28, 29, 30, 31, 32, 33, 34, 35, 40,
44, 47, 58, 66, 88, 93, 113, 114, 122
Immunogen, 26, 82, 88
Immunogenic, 15, 28, 29, 30, 31, 32, 33, 82, 84, 88, 89, 122
Immunoglobulin, 19, 20, 21, 25, 26, 27, 28, 32, 34, 41, 50, 66, 69, 101, 113,
116, 123, 125; see also antibody
Immunoisolation, 28, 85
Immunoradiometric assay, 33
Immunoreactivity, 7, 9, 20, 28, 52, 88
Immunosuppression, 30, 31
Immunotoxin, 30, 54
Impact hemolysis, 138
Impedance mismatch, 133
Implant infection, 10
Imuran, 30
Incontinence, 68, 74, 107
India ink, 28, 41, 45, 46, 61, 65, 66, 67, 101, 102, 105, 108
India ink particle, 41, 66, 105, 108
Indigestible particle, 108, 109, 121
Indole, 112
Indoleamine 2,3?dioxygenase (IDO), 33
Induce exocytosis of phagosomal vacuole, 118
Inductively Coupled Plasma Mass Spectroscopy (ICP-MS), 54
Inductively Coupled Plasma?Atomic Emission Spectrometry, 81
Inert particle, 81, 94, 100, 103, 104, 105, 107, 121
Inflammation, 5, 6, 7, 11, 19, 20, 24, 29, 30, 32, 33, 35, 36, 37, 40, 42, 44,
45, 47, 49, 51, 53, 54, 56, 62, 63, 64, 65, 66, 67, 68, 70, 71, 72, 73, 74,
77, 79, 80, 82, 83, 86, 94, 95, 100, 103, 122, 123, 127, 128, 129, 132, 134,
135, 142, 156
Inflammatory cell, 8, 18, 24, 36, 67, 76, 78, 104, 107, 111
Inflammatory disease, 88, 158
Inflammatory lung disease, 4
Influenza, 25, 34, 84, 95, 114, 117, 119
Ingber, Donald, 18
Ingested particle, 63, 102, 105, 119
Ingestion burden, 160
Inhaled particle, 6, 65, 79, 106, 123
Inhibit enclosure and scission, 117
Inhibit phagocyte metabolism, 119
Inhibit phagocytic engulfment, 112, 116
Inhibit phagolysosomal fusion, 119
Inhibitor of apoptosis, 114, 142, 153
Ink particle, 41, 66, 102, 105, 108
Inositol trisphosphate, 130, 131
Institute for Molecular Manufacturing (IMM), preface
Integration, 10, 17, 18, 53, 111, 149
Integrin, 13, 16, 63, 82, 113, 114, 135, 136, 140
Integrin associated protein (IAP), 114, 142
Intercellular adhesion, 136, 150
Interface adhesion, 153, 154
Interferon, 20, 21, 33, 45, 131
Interleukin, 20, 21, 31, 45, 53, 60, 82, 110, 120, 160; see also IL-
Intermediate filament, 149, 150, 151, 152
Intermembrane inclusion bodies, 160
Interstitium, 5, 67, 79, 86, 103, 106, 107
Intestinal bacteria, 106
Intestine, 1, 3, 22, 42, 94, 95, 97, 99, 106, 126, 127, 146, 155, 156
Intracellular bacteria, 21, 118, 119
Intracellular cavitation, 145, 152
Intracellular crystal, 159, 160, 161
Intracellular lipofuscin and storage diseases, 159
Intracellular locomotion, 149, 151
Intracellular microbiota, 160
Intracellular microspheres and crystals, 160
Intracellular microzones, 145, 153
Intracellular nanorobot intrusiveness, 161
Intracellular nuclease, 82
Intracellular particle, 63, 148, 149, 152
Intrauterine, 133
Intravasation, 128
Intravascular electrode, 143
Intravascular hemolysis, 138, 139
Intravitreous, 66, 104
Intrinsic pathway, 38, 40
Intrusiveness, 155, 156, 157, 158, 159, 160, 161
Inulin, 23
Iodination, 98
Ionophore, 118
IpaB, 119, 120
Ipecac, 42
Iridium, 85, 123
Irino, S., 96
Iron, 2, 5, 6, 42, 45, 56, 75, 86, 90, 101, 105, 138, 149, 160
Iron oxide particle, 101, 105, 160
Iron particle, 86
Ischemia, 98, 123, 134, 142, 156
Isenberg, G., 131
ISFET, 145
Islet cell, 33, 159
Isoelectric, 14, 23, 75, 145
Isoprenaline, 139
1?(5?isoquinolinesulfonyl) piperazine, 113
Isotonic, 68, 138, 158, 159
Isotype, 27, 58
ITAM, 116
Itching, 2, 19, 34, 90, 112, 125, 126, 155; see also pruritis
IUD, 10, 133
Izhaky, David, 28
J
Jacobstein, Neil A., preface
Jani, P., 105
Jejunal, 127
Jejunum, 42
Jiggling, 154
Johnson & Johnson, 9
Jones, M.I., 51
Jones, O.T., 53
Joseph Brain, 55
Josset, Y., 78
Jurkat cell, 136
K
K antigen, 117
Kainate, 61
Kallikrein, 24, 35, 36, 38
Kaolin, 35, 38, 109, 145
Kaolin(ite) particle, 35, 145
Kartagener syndrome, 151
Kekich, David A., preface
Keloid, 47
Kenacid Blue, 51
Keratin, 150
Keratinocytes, 9, 18, 32, 57, 60, 82, 89, 144, 150
Keratitis, 10, 32
Keratocyte, 104
Keratomileusis, 37
Kerosene, 88
Kessler, N., 28
Ketoconazole, 112
Ketotifen, 112
Kidney, 11, 18, 34, 36, 45, 51, 58, 59, 66, 74, 79, 84, 93, 94, 97, 99, 101,
103, 105, 106, 112, 123, 138, 151, 158
Kidney vasculature, 97, 103
Kinase, 59, 113, 115, 116, 130, 131, 147
Kinase inhibitor, 113, 115, 116
Kinesin, 97, 147, 151, 152, 153, 154
Kinetochore, 151
King, Benjamin T., 69
Kinin, 24, 35, 36, 37
Kirschner wire, 93
Klebsiella pneumoniae, 117
Klockars, Matti, 6, 53
Knowles pin, 93
Kofler, N., 105
Komender, J., 81
KP1, 76
Kreyling, W.G., 123
Krummenacker, Markus, preface
Kumar, Aryavarta, preface, 29, 40
Kupffer cell, 66, 73, 75, 98, 99, 101, 102, 103, 115, 116, 120, 121, 122, 123,
161
KurzweilAI.net, preface
Kurzweil, Raymond, preface
Kwon, Eugene, preface
Kyotorphin, 86
L
Laber, Emily, preface
Lactoferrin, 45
Lactose, 17
Lademann J., 127
Lahann, Joerg, 19
Lamellipodia, 18, 116, 118
Laminin, 13, 16, 70, 71, 85, 86, 160
Landes Bioscience, preface
Landes, Ronald G., preface
Langenback, E.G., 107
Langer, Art, 55
Langerhans cells, 22, 104, 110
Langmuir (film), 14
Large particle, 4, 93, 94, 105, 115, 116, 117
Large particle movement, 93
Latex bead, 104, 105, 112, 115, 119, 123, 160
Latex particle, see particles
Laurent, Christophe, preface
Lauwerys, R., 6
LD50, 58, 60, 157, 158
LDH, 67, 68
LDL, 33, 86, 100
Leach, 7, 46, 81, 83, 89, 110
Leachates, 83, 88, 89
Lectin pathway, 22
LeFevre, M.E., 105, 106
Leflunomide, 30
Legionella pneumophila, 118, 119
Leishmania, 35
Leitl, Eugene, preface
Lemler, Jerry B., preface
Leukapheresis, 140
Leukergy, 94
Leukocidin, 120
Leukocyte, 6, 10, 13, 18, 20, 21, 22, 23, 32, 33, 34, 38, 40, 53, 54, 57, 62,
63, 66, 67, 70, 73, 82, 86, 94, 98, 99, 101, 103, 104, 106, 110, 112, 113, 115,
116, 118, 125, 130, 132, 135, 136, 137, 140, 141, 142, 143, 144, 145, 146, 156,
159, 160, 161
Leukocyte adhesion, 63, 135
Leukocyte aggregation, 132, 140, 142
Leukocyte margination and migration, 140, 141
Leukocyte surface fluctuations and elasticity, 141
Leukocytolysis, 140
Leukocytosis, 73, 140
Leukocyturia, 104
Leukoembolization, 94, 142
Leukostasis, 132
Leukotriene, 28, 40, 160
Leveen, H.H., 71
Lewandowska?Szumiel, M., 81
Lewis, James B., preface
Lewy bodies, 159
LeX, 32
LFA (lymphocyte function?associated antigen), 136
LGL, 20
Lice, 127
Lidocaine, 115
LifeCell Corp., 143
Lin, J.C., 58
Lin, H.Y., 8
Lin, Y., 31
Linder, S., 51
Linker, Charles A., 96
Lipase, 113, 115, 160
Lipid, 6, 15, 16, 22, 23, 25, 33, 52, 54, 56, 57, 58, 61, 69, 74, 86, 88, 95,
98, 101, 102, 115, 118, 120, 136, 139, 143, 144, 146, 147, 148, 152, 159, 160
Lipid bilayer, 16, 23, 25, 33, 54, 56, 57, 115, 118, 136, 139, 144, 146, 147,
148
Lipid bilayer membrane demixing, 144
Lipofuscin, 149, 159, 161
Lipofuscinosis, 149, 159
Lipoma, 45
Lipophilic, 86, 112, 127, 148
Lipopolysaccharide (LPS), 22, 23, 25, 31, 38, 43, 44, 45, 70, 114, 117, 119,
144
Lipoprotein, 14, 23, 71, 86, 159
Liposome, 11, 14, 15, 56, 57, 60, 73, 87, 94, 101, 108, 116, 117, 144
Liposome particle, 116
Lipoxin, 112
Lison, D., 6
Lissencephaly, 149, 151
Listeria ivanovii, 118
Listeria monocytogenes, 34, 35, 118, 119, 120, 121, 149, 161
Listeriolysin O, 118, 121
Listeriosis, 121
Lithophagy, 3
Lithotripsy, 45
Liver, 14, 20, 22, 31, 32, 33, 38, 45, 56, 57, 58, 59, 66, 67, 68, 73, 74, 79,
82, 88, 93, 94, 95, 97, 98, 99, 100, 101, 102, 103, 105, 106, 107, 108, 116,
119, 120, 123, 138, 156, 159, 161
Liver vasculature, 94, 101
Load error, 44
Logajan, James, preface
Long?circulating, 15, 86, 114
Loperamide, 86
Loratadine, 41
Lou Gehrig’s disease, 61
Low esophageal sphincter pressure, 74
Low temperature isotropic carbon, 62
LPS, see lipoopolysaccharide
LSP1, 113
LTI, 62, 63, 64, 68
LTIC, 38, 62, 63, 142
Lumbrokinase, 13
Lung, 4, 5, 6, 40, 45, 46, 47, 53, 55, 56, 67, 68, 71, 79, 80, 93, 94, 101,
102, 105, 106, 107, 108, 109, 113, 120, 123, 156, 157, 160
Lung burden, 67, 107
Lung clearance, 67, 106, 107
Lung vasculature, 94, 101
Lupus, 23, 82, 122
LVAD (left ventricular assist device), 38, 52, 78
Lymnaea, 136
Lymph node, 5, 22, 30, 64, 66, 68, 73, 74, 79, 93, 95, 99, 100, 103, 104, 105,
106, 107, 108, 109, 114, 121, 122, 129, 157
Lymphadenopathy, 41
Lymphangitis, 129
Lymphatic, 5, 7, 22, 30, 32, 35, 65, 66, 73, 74, 79, 84, 93, 95, 97, 98, 99,
100, 101, 103, 104, 105, 106, 107, 108, 109, 114, 122, 127, 128, 129, 161
Lymphatic vessel, 35, 79, 84, 108, 128
Lymphedema, 129
Lymphoblastoid cell, 108
Lymphocompatible, 70
Lymphocyte, 20, 21, 22, 23, 24, 25, 30, 31, 32, 33, 34, 40, 41, 58, 59, 60,
66, 68, 70, 73, 74, 78, 79, 81, 86, 95, 98, 99, 100, 103, 104, 107, 108, 113,
114, 115, 118, 120, 136, 140, 141, 142, 144, 159, 161
Lymphocytopenia, 121
Lymphokine, 31, 41, 44, 79, 103, 120
Lymphoma, 11
Lysosome, 34, 53, 81, 98, 104, 118, 119, 123, 149
Lysozyme, 19, 67, 75, 98, 99, 100, 112
M
M protein, 25, 34, 117
Mab (monoclonal antibody), 25, 28, 29, 30, 31, 36, 39, 46, 59, 79, 87, 113,
147
MAC, 20, 22, 23, 24, 25
Mace, Patrick, preface
Macromolecular cross?interface adhesion, 153
Macrophage, 4, 5, 6, 7, 10, 11, 13, 14, 16, 17, 18, 19, 20, 21, 22, 23, 24,
27, 31, 33, 34, 35, 36, 37, 41, 43, 45, 46, 51, 53, 54, 55, 56, 57, 58, 63,
64, 65, 66, 67, 68, 69, 72, 73, 75, 77, 78, 79, 80, 86, 87, 95, 98, 99, 100,
101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116,
117, 118, 119, 120, 121, 122, 123, 127, 137, 142, 143, 145, 146, 148, 149, 159,
160, 161
Macrophage inflammatory protein, 45; see also MIP
Macula densa cell, 103
Magnesium urate, 28
Magnetic resonance imaging, see MRI
Magnetite, 86, 103
Maillard reaction, 143
Major histocompatibility complex, see MHC
Malaria, 35, 95, 120, 161
Malik, N., 84
Manganese, 54, 123
Mannitol, 86
Mannose, 20
Mannosidosis, 159
Mannosylate, 115
Marathon, 138, 157
Marburg, 128
March hemoglobinuria, 138
Marchant, Roger E., preface, 14, 15
Margination, 101, 111, 140, 141
Marmoset, 127
Maroto, Rosario, 147
Marsupialization, 18, 110, 111, 122
Martensite, 83
Martial arts, 138
Martinac, Boris, 148
Mast cell, 24, 26, 28, 38, 40, 41, 45, 67, 137
Mathews, Elizabeth, preface, 2
Mathiowitz, E., 106
Matouschek, E., 74
Matrix metalloproteinase (MMP)?1, 131
Matsuhashi, M., 64
Mattson, M.P., 57
Mausle, E., 80
Mawn, L.A., 78
Maxwell, J.C., 89, 90
McCrone’s Particle Atlas, 2
McKendree, Thomas, preface
MCP (membrane cofactor protein), 24, 25
MCP?1 (monocyte contact protein), 110
MCP?2 (monocyte contact protein), 110
McQuillan, James, preface
MCV (mean cell volume), 96
MDCK (Madin?Darby canine kidney) cells, 18
Mechanical adhesion, 64
Mechanical cell membrane disruptions, 146
Mechanical cellular trauma, 153
Mechanical cytoskeleton disorganization, 149
Mechanical damage, 1, 4, 6, 128, 129, 134, 135, 137, 146, 150
Mechanical damage from ingested diamond, 1
Mechanical damage to extracellular matrix proteins, 137
Mechanical disruption of intracellular microzones, 153
Mechanical hemolysis, 138
Mechanical interaction with human integument, 125
Mechanical interactions with cytoskeleton, 149
Mechanical interactions with erythrocytes, 137
Mechanical interactions with glycocalyx, 137, 145
Mechanical interactions with leukocytes, 140
Mechanical interactions with platelets, 139
Mechanical irritation, 5, 42, 125
Mechanical shearing, 135, 138, 140
Mechanical shock, 44, 134
Mechanical signal transduction, 150
Mechanical strain, 87, 131, 135, 136, 137, 150
Mechanical trauma, 36, 44, 47, 118, 127, 134, 138, 141, 149, 153
Mechanically?induced proteolysis, apoptosis, or prionosis, 153
Mechanocompatibility, 125, 129, 135, 137, 145, 146, 154
cytomembrane and intracellular mechanocompatibility, 125, 145
cytopuncture and membrane resealing, 146, 147
disruption of molecular motors and vesicular transport, 151
viability of confined, pressurized, or desiccated cells, 142
Mechanocompatibility with nontissue cells, 137
Mechanocurrent, 136
Mechanoelectric, 144
Mechanoenzyme, 117
Mechanoreceptor, 42, 126, 131
Mechanosensitivity, 131, 135, 136, 137, 147, 148
Mechanosensor, 42, 126, 136
Mechanosynthesis, 122
Mechanotransducer, 148
Mechanotransduction, 135
Meclizine, 43
Medawar, P.B., 32
Medical University of Warsaw, 55
Medtronics, 9
Medulla oblongata, 42
Medullary midline, 43
Megakaryocyte, 161
Melanocortin, 46
Melanosome, 123
Melittin, 16
Mellitic acid, 64
Membrane adhesion, 140
Membrane affinity, 148
Membrane elasticity and cellular expansion, 159
Membrane fluidizer, 119
Membranolytic, 83
Memory tape (fluorocarbon), 68
MEMS (microelectromechanical systems), 4
Meningeal cell, 105
Meningitis, 25, 34, 60, 66, 71, 86, 114
Mercaptoethanol, 24
6?mercaptopurine, 30
Mercury, 1, 42, 109
Meretei, Attila, preface, 155, 157
Merkle, Ralph C., preface, 122
Merril, C.R., 114
Mesangial, 99, 103, 150
Mesangium, 67, 97, 103
Mesenchymal, 78, 80, 122, 137, 143
Mesentery(-ic), 104, 105, 106, 140
Mesothelioma, 5, 47, 55
Messenger molecule, 143
Metal particle, 56, 83, 109
Metals, 5, 6, 9, 16, 41, 47, 55, 56, 61, 66, 68, 74, 81, 83, 84, 85, 110, 144
Metamorphic, 18, 19, 56, 96, 114, 126, 128, 153
Metamorphic hypodermic injection carrier, 128
Metaplasia, 64
Methadone, 113, 115
Methanofullerene, 58
Methoxypoly(ethylene glycol) (mPEG), 31
Ethylene glycol, 14
Methylpalmitate, 116
Methylprednisolone, 113
Metoclopramide, 43
MetroLine Industries, Inc., 13
Metronidazole, 112
Metrorrhagia, 133
MHC (major histocompatibility complex), 20, 21, 22, 29, 30, 31, 33, 34, 35,
89
MIC, 34
Mice, 22, 28, 32, 33, 41, 46, 47, 51, 56, 58, 59, 60, 61, 66, 67, 68, 70, 71,
72, 73, 79, 80, 84, 100, 102, 103, 104, 105, 106, 107, 108, 110, 114, 121, 156,
157, 158
Micelle, 58, 84
Miconazole, 112
Microangiopathy, 135, 138, 140
Microautophagocytosis, 149
Microbead, 68, 101, 161
Microbial adhesion, 79
Microbivore, 43, 44, 94, 122, 162
Microelectrode, 85, 147
Microfilament, 60, 78, 115, 116, 119, 129, 130, 149, 150, 151
Microfilariae, 135
Microglia, 86, 99, 104, 105, 115
Microgravity, 150
Microhemorrhage, 66
Microinjection, 147, 153
Microparticle, 65, 67, 80, 87, 94, 98, 100, 101, 103, 104, 105, 106, 107, 127,
145, 158, 159
Micropinocytosis, 22, 101
Micropipette, 136, 141, 147, 148, 149, 159
Microsome, 56, 57, 59, 98, 123
Microsphere, 4, 17, 74, 93, 94, 96, 97, 100, 101, 102, 103, 104, 105, 106, 107,
108, 112, 115, 117, 127, 140, 145, 150, 151, 158, 159, 160
Microspherocyte, 138
Microtubule, 51, 60, 116, 117, 118, 130, 132, 148, 149, 150, 151, 152, 154
Microtubule binding site, 151
Microtubule?associated protein, 151
Microvilli, 95, 117, 137, 140, 147
Microvillus, 141
Microzone, 119, 120, 145, 153
MIF (migratory inhibition factor), 112
Migraine, 43
Migration of particle, 74
Miliaria, 125
Miller, Gina “Nanogirl”, preface
Millstein, Larry S., preface
MION, 86
MIP, 22, 45; see also macrophage inflammatory protein
Mismatch, 110, 126, 133, 148
Mitochondria, 39, 59, 60, 78, 98, 120, 123, 128, 142, 148, 149, 152, 153, 160,
161
Mitochondrial crystalline inclusions, 160
Mitochondrion, 15, 148, 160, 161
Mitogen, 54, 82, 130, 132, 144
Mitomycin?C, 31
Mitosis, 30, 83, 99, 109, 142, 148, 149, 151
Miyata, N., 57
MMA?C60, 59
Mn, 131
MNP, 98, 99
MNT, 49
Modulation of endothelial phenotype and function, 129, 130, 131
Molecular manufacturing, 17, 52, 138, 14
Molecular mimicry, 32, 114
Molecular motors, 151
Molecular recognition, 26
Molecular sorting rotor, 19, 25, 29, 36, 41, 44, 46, 87, 110, 119, 126, 134,
142, 143, 145, 146, 153
Molybdenum, 5, 54
Monkey, 43, 67, 70, 71, 76, 78, 104, 113
Monocyte, 6, 7, 18, 20, 24, 27, 31, 34, 36, 45, 51, 53, 54, 57, 59, 60, 66,
69, 74, 80, 98, 99, 100, 101, 103, 104, 108, 109, 110, 111, 112, 113, 114, 115,
117, 120, 121, 123, 140, 141, 142, 159, 160
Monolayer, 11, 13, 14, 15, 16, 17, 18, 19, 29, 39, 50, 61, 69, 71, 76, 78, 80,
123, 129, 130, 134, 140, 160
Mononuclear phagocyte, 14, 26, 44, 66, 67, 96, 98, 99, 101, 104
Mononucleosis, 156
Monosodium, 23, 28, 36, 45, 53, 156
Monosodium urate, 23, 28, 36, 45, 53, 156
Moraxella catarrhalis, 144
Morcellation, 68
Morgan, Ron, 55
Morphine, 113, 115
Morphogen, 111, 150
Morris, Kelly, preface
Mossman, Brooke, 55
Mouse, 32, 40, 41, 46, 47, 51, 55, 56, 57, 58, 59, 66, 67, 68, 71, 78, 80, 82,
96, 102, 103, 104, 106, 107, 108, 115, 117, 122, 123, 136, 142, 143, 157, 160
Mouse blood, 82
Mouse police, 157
mPEG, 31
MPS, 99
MRI, 61, 156
MRNA, 82, 83, 130, 142, 143, 144
MSAD?C60, 58, 60
MSDS, 2, 66
MSU, 156
MSUM, 53
Mucoadhesivity, 17
Mucociliary, 4, 5, 106, 127
Mucociliary escalator, 5, 106, 107
Mucopolysaccharide, 38, 76, 103, 110
Mucoprotein, 138
Mucormycosis, 121
Mucosacompatibility, 125, 126
Mucus, 4, 26, 27, 40, 42, 127
Mukhopadhyay, Rajendrani, preface
Muller cell, 67
Murad, K.L., 31
Murine, 11, 21, 51, 65, 99, 100, 103, 104, 105, 108, 112, 113, 115, 136, 141,
160
Murray, Robert K., 26, 27
Muscarinic, 43
Muscle cell, 32, 33, 59, 85, 103, 114, 129, 130, 131, 132, 135, 147, 150, 159,
161
Muscular dystrophy, 137, 150
Mutagen, 46
Mutagenesis, 82
Mutagenic, 5, 7, 11, 46, 52, 57, 58, 67, 78
Mycobacterium leprae, 31, 34
Mycobacterium microti, 35
Mycobacterium tuberculosis, 31, 34, 35, 60, 113, 119, 120
Mycophenolate mofetil, 30
Mycophenolic acid, 30
Mycotoxin, 115
Myeloblast, 51
Myeloma, 159
Myeloperoxidase, 98
Myeloproliferative disorder, 161
Myoblast, 33, 144
Myocardial infarction, 43, 67, 123, 131, 142
Myocardial necrosis, 97
Myocardium, 37, 43, 67, 97, 123, 131, 142, 149, 158
Myocyte, 120, 136, 147, 149, 150, 153, 160
Myoma, 157
Myopia, 156
Myosin, 75, 96, 116, 118, 151, 152, 153
Myosin inhibitor, 118
Myxococcus xanthus, 112
N
N?(2?hydroxypropyl) methacrylamide (HPMA), 85
N?acetyl glucosamine, 17
N?acetyl heparosan, 32
N?acetyl?PGP, 113
N?acetylglucosaminidase, 123
N?butanol, 119
N?chlorotaurine, 112
NADH, 144
Nakanishi, I., 61
Nakashima, Y., 80
Nanoaggregate, 110, 125, 133, 134, 135, 138, 140, 142, 144, 152, 154
Nanocannula, 126, 135
Nanocatheter, 126
Nanocrit (Nct), 53, 54, 58, 81, 89, 90, 99, 100, 123, 132, 133, 139, 146, 154,
158
Nanocrystal, 29, 83, 84, 160
Nanoerythrosome, 15
Nanoid shock, 43
Nanomedical material, 49, 81
Nanomedicine, 20, 23, 24, 30, 31, 45, 49, 82, 84, 93, 122, 125, 155, 14
Nanomedicine Art Gallery, preface
Nanoparticle, 14, 15, 19, 24, 56, 83, 84, 86, 87, 101, 103, 114, 123, 160, 161
Nanopill, 61
Nanopyrexia, 44, 45
Nanorobot, 1, 2, 4, 7, 10, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 23, 24, 25,
28, 29, 30, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47,
49, 50, 51, 52, 53, 54, 55, 57, 60, 61, 64, 66, 67, 68, 75, 76, 79, 80, 81,
82, 83, 86, 87, 88, 89, 90, 91, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103,
104, 105, 106, 107, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120,
121, 122, 123, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137,
138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153,
154, 155, 156, 157, 158, 159, 160, 161, 162
Nanorobot adhesion, 13
Nanorobot binding site, 29, 87, 146
Nanorobot biofouling, 81, 87, 88
Nanorobot convoy formation, 129
Nanorobot distribution and phagocytosis, 93
Nanorobot fragments, 89, 93, 122, 123
Nanorobot immunoreactivity, 20
Nanorobot mechanocompatibility, 125, 154
Nanorobot non-adhesion, 13, 14
Nanorobot volumetric intrusiveness, 155
Nanorobot?nanorobot mechanocompatibility, 125, 154
Nanorobotic concussive vasculopathy, 134
Nanorobotic destructive mechanical vasculopathies, 132
Nanorobotic hemolysis, 138
Nanorobotic lacerative vasculopathy, 133
Nanorobotic obstructive mechanical vasculopathy, 132
Nanorobotic organ, 16, 19, 32, 41, 46, 50, 93, 110, 111, 131, 133, 141, 154
Nanorobotic ulcerative vasculopathy, 133
Nanosecretagoguery, 140
Nanosensor, 119
Nanoshell, 84
Nanosieve, 87
Nanotechnology, 17, 55, 81, 84, 162
Nanotube, 13, 28, 36, 46, 55, 56, 57, 58, 59, 60, 61, 75, 84, 85, 144, 148
NASA, 55, 56
Natural cell membrane wounding, 146, 147
Natural killer cell (NK), 20, 24, 26, 27, 29, 34, 35, 45, 103, 114, 153
Nausea, 40, 42, 43, 87, 125, 126, 158
Nauseogenesis, 42, 43, 125
Navicyte, 110
NBT, 112
Nct, see nanocrit
Necrosis, 5, 20, 21, 24, 35, 36, 43, 45, 60, 62, 65, 66, 77, 79, 80, 85, 95,
97, 105, 109, 111, 113, 120, 121, 126, 128, 133, 134, 144, 160
Necrotaxis, 112
Neisseria gonococci, 25
Neisseria gonorrhoeae, 25, 34, 95, 119
Neisseria meningitidis, 25, 34, 95
Neon gas pump, 122
Neonatal, 30, 66, 78, 85, 104
Neoplasm, 45, 46, 47, 67, 82
Neoplastic growth, 47, 132
Nephritis, 122
Nephrolithiasis (kidney stones), 45, 103
Nephrotoxicity, 30
Netrin, 112
Neural cells, 71, 85, 87, 112, 137
Neural crest cell, 144
Neuralgia, 71
Neurite, 17, 57, 85, 152
Neurofibroma, 72
Neuroglial, 104
Neurohypophysis, 87
Neuron, 17, 18, 42, 43, 57, 60, 61, 71, 85, 87, 89, 113, 114, 118, 131, 135,
136, 144, 147, 148, 150, 151, 152, 153, 156, 159
Neuronal ceroid?lipofuscinosis (NCL) disease, 159
Neuropeptide, 32, 36, 42
Neuropil, 86, 87, 104
Neurotensin, 125
Neutropenia, 121
Neutrophil, 4, 5, 13, 14, 18, 20, 24, 25, 27, 32, 33, 36, 40, 45, 46, 51, 53,
60, 63, 65, 66, 67, 68, 69, 70, 76, 77, 78, 80, 98, 99, 100, 101, 103, 104,
107, 108, 109, 110, 112, 113, 114, 115, 116, 118, 120, 121, 122, 123, 127, 132,
136, 137, 140, 141, 146, 147, 159, 160, 161
Neutrophil aggregation, 40
Neutrophil lifespan, 146
Newspaper dust, 42
NFPA, 122
Nichrome, 85
Nickel, 41, 54, 68, 83
Niemann?Pick disease, 159
Nifedipine, 136
Nigericin, 112
Nishio, K., 80
Nitinol, 81, 83, 85
Nitric oxide, 36, 39, 55, 59, 61, 94, 131
Nitric oxide synthase, 61
Nitroimidazole, 112
Nitrosylation, 123, 160
Niu, Chunming, 55
NK, 20, 24, 26, 27, 29, 34, 35, 45, 103, 114, 153
Nkamgueu, E.M., 80
NKG2D, 34
nNOS, 61
NO, 55, 94, 123, 135
Nocardia, 119
Nocardiosis, 121
Nociception, 156
Nociceptor, 35, 36, 125, 126, 127, 137, 156
Nocodazole, 130, 150
Non?occluding indwelling vascular obstructions, 135
Noncovalent adhesion, 153, 154
Nonimmunogenic, 28, 29, 31, 82, 89, 146
Nonopsonic phagocytosis, 117
Nonspecific adhesion, 14
Nonspecific (innate) immune response, 20
Nonspecific aggregation, 154
Nonspecific inflammation, 20, 35
Nontissue cell, 125, 137, 146
Noradrenalin, 121
North Carolina State University, 16
NSAID, 36, 42, 45
Nuclear envelope, 149
Nuclear extrusion, 118
Nuclear membrane, 149, 152
Nuclear pore, 85
Nuclear transfer, 33
Nuclear transplantation, 159, 161
Nuclease, 82, 149
Nucleus, 43, 44, 45, 47, 53, 84, 98, 100, 101, 118, 136, 143, 145, 147, 149,
150, 151, 152, 159, 161
Nucleus tractus solitarius, 43
Nurse cell, 161
Nygren, H., 63
O
O antigen, 117
O?antigen, 25, 114
O2, 8, 16, 50, 56, 70, 112, 120, 146, 153, 156
O3, 56, 68
Oberdorster Gunter, 123, 160
Obstructive pulmonary disease, 128
Octadecylamine, 58
O’Donnell, B., 74
O’Leary, A., 51
Oligodeoxynucleotide, 82
Oligomaltose, 15
Oligonucleotide, 61, 82, 85
Oligopeptide, 16, 21
Oligosaccharide, 14, 15, 25, 146
Oliguria, 104
Olliver, Vik, preface
Omentum, 104
Ondansetron, 43
Oocyte, 118, 123, 137, 147, 153
Oonishi, H., 80
Opioid, 43, 113, 115
Oppenheimer effect, 47
OPSI, 95
Opsonin, 13, 23, 36, 98, 101, 115, 117
Opsonin?independent phagocytosis, 117
Opsonization, 14, 21, 24, 25, 53, 99, 100, 101, 102, 114, 117, 122
Opsonophagocytosis, 115
Optical tweezer, 136
Optode, 147
Organelle membrane breach, 146, 148
Orthodontic, 83
Orthopedic, 7, 8, 9, 52, 71, 77, 78, 81, 155
Orthopedic biomaterials, 8
Oscillating electric/magnetic field, 144
OSHA, 80, 157
Osmotic, 12, 23, 35, 44, 86, 87, 129, 152, 159
Osmotic disruption, 86, 87
Osmotic pressure, 35, 129
Osseocompatibility, 65
Osseointegration, 8, 16, 17, 52, 63, 76, 111
Osteoblast, 17, 46, 51, 78, 80, 83, 111, 136, 142, 144, 150
Osteoblast adhesion, 78
Osteoclast, 78, 83, 98, 111, 144
Osteocyte, 76, 136
Osteodystrophy, 81
Osteogenesis, 51, 70, 111
Osteolysis, 8
Osteonectin (ON), 79
Osteopontin (OP), 19, 79, 136
Osteoporosis, 59
Otosclerosis, 72
Ottoman Empire, 1
Outmessaging, 125
Ovalbumin, 28, 66, 75
Ovary, 32, 44
Overbury, Sir Thomas, 1
Overview of the human immune system, 20
Owens, Erik L., 132
Oxalate crystal, 103
Oxatomide, 41
Oxygen, 5, 6, 16, 26, 46, 47, 50, 53, 55, 56, 57, 58, 60, 61, 66, 69, 71, 74,
76, 83, 88, 95, 98, 103, 114, 119, 120, 122, 128, 132, 134, 139, 144, 145, 146,
149, 150, 158
Oxypherol, 72
Ozone, 26, 68, 74
P
Paatsch, Brett, preface
PACAP?38 (pituitary adenylate cyclase activating peptide), 112
Pacemaker, 7, 155
Paclitaxel, 132
PAF, 36; see also platelet activating factor
PAH, 57, 66, 79
Pain, 1, 2, 5, 8, 9, 35, 36, 38, 41, 42, 66, 71, 74, 81, 110, 125, 126, 127,
128, 137, 147, 150, 155, 156
Palladium, 18, 41, 83, 85
PALS, 95
PAM, 106, 107
PAMAM, 84
Pancreas, 84, 94, 97
Pancreatic islet cell, 159
Pancreatitis, 42
Pannus, 7
Papain, 125
Parabrachial nucleus, 43
Paracelsus, 1
Paraffin, 122
Parainfluenza, 119
Paramecia, 112
Paratope, 29, 30
Parenchyma, 4, 33, 63, 65, 71, 73, 86, 102, 105, 134, 145
Paresthesia, 150
Parkinson’s disease, 61, 85, 149
Parsley cell, 150
Particle, 1, 2, 3, 4, 5, 6, 7, 8, 11, 12, 14, 15, 21, 23, 24, 27, 28, 35, 36,
37, 38, 41, 42, 45, 46, 47, 49, 52, 53, 54, 55, 56, 58, 62, 63, 64, 65, 66,
67, 68, 69, 72, 73, 74, 75, 79, 80, 81, 83, 84, 85, 86, 87, 89, 90, 93, 94,
95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111,
112, 114, 115, 116, 117, 118, 119, 121, 122, 123, 126, 127, 132, 133, 140, 141,
144, 145, 147, 148, 149, 152, 155, 156, 157, 158, 160, 161
Particle aggregation, 14, 73
Particle burden, 4, 107, 108, 109, 160
Particle clearance, 103, 104, 107, 121
Particle clearance from nonsanguinous spaces, 104
Particle clearance from the lymphatics, 103, 107
Particle migration, 73, 74
Particle trapping, see geometrical trapping
Particle, latex 45, 102, 106, 112, 115, 122, 158, 160
Particulate burden, 157
Parvovirus, 121
Passaro, Peter, preface
Pasteurella multocida, 29
Patch clamp, 137, 147
Patella, 62, 64
Pathogenic bacteria, 34, 114, 117
Patocytosis, 100, 117
Patterned surface, 17, 18, 85
Pauling scale, 50
Paxillin, 116
PBCA, 86
PBMC, see peripheral blood mononuclear cell
PCV (postcapillary venules), 66, 108
PDGF, 45, 131; see also platelet-derived growth factor
PDMS, 18
Peacock, Erle E., Jr., 110
PEBBLE, 84
PECAM?1 (platelet?endothelial cell adhesion molecule-1), 116, 130
Pecht, Israel, 28
Pediculosiss, 125, 127
PEG, see poly(ethylene glycol)
Pegylate(-ion), 14, 29, 31, 86, 102, 114
PEI, 85
Pelikan ink, 108
Penicillin, 41, 88
PEO, 14, 24, 84
Pepper particle, 5
Peptidase, 113, 125
Peptide, 13, 14, 16, 17, 20, 21, 22, 24, 25, 29, 31, 34, 35, 39, 56, 57, 59,
60, 61, 82, 84, 85, 86, 87, 89, 112, 113, 139, 148, 153
Peptide nucleic acid, 82
Percussive, 134
Perfluoroalkoxy, 71
Perforation, 1, 3, 4, 42, 44, 45, 72, 125, 127, 134, 138
Pericyte, 98, 105, 108
Peripheral blood mononuclear cell (PBMC), 31, 33, 60
Peristalsis, 126, 127
Peristaltogenesis, 125, 126
Peritoneum, 55, 73, 79, 104, 107
Peritonitis, 3, 45, 66, 127, 156
Peroxidation, 6, 56, 57, 61, 159, 160
Peroxide, 53, 61, 67, 82, 98, 112
Peroxisomal, 147, 149
Persantine, 39
Pertussis, 113, 115, 120
Pertussis toxin, 113, 115, 120
PET, 17
Peterson, Christine L., preface
PEU, 17
Peyer’s patches, 22, 67, 105, 106, 107, 127
Peyronie’s disease, 72
PGE2, 103, 136
PHA, 31
Phage, 114, 161
Phage particle, 111, 114, 161
Phage therapy, 114
Phagocyte, 10, 13, 14, 20, 21, 26, 34, 44, 62, 65, 66, 67, 73, 85, 96, 98, 99,
100, 101, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116,
117, 118, 119, 120, 121, 122, 123, 132, 140, 144, 145, 160, 161
Phagocyte adhesion, 116
Phagocyte avoidance and escape, 98, 111, 122
Phagocyte ingesta, 160
Phagocytes, phagocytosis, and the RES, 98
Phagocytic, 112
Phagocytocide, 120
Phagocytose bacteria, 119, 122
Phagocytosis, 11, 21, 22, 23, 27, 34, 36, 45, 53, 64, 65, 66, 67, 68, 70, 79,
80, 85, 93, 96, 98, 99, 100, 101, 102, 103, 104, 106, 107, 111, 112, 113, 114,
115, 116, 117, 118, 132, 139, 142, 144, 145, 149
Phagocytosis and opsonization in blood, 101
Phagocytosis in kidney vasculature, 103
Phagocytosis in liver vasculature, 101
Phagocytosis in lung vasculature, 101
Phagocytosis in spleen vasculature, 103
Phagocytosis of bacteria, 142
Phagocytosis of bloodborne microparticles, 100
Phagocytosis of medical nanorobots, 98
Phagolysosome, 81, 98, 101, 119
Phagosome, 53, 98, 100, 101, 112, 116, 117, 118, 119, 122
Pharmacokinetic, 60
Pharmacyte, 44
Phelps, P., 53, 54
Phenol, 112
Phenothiazine, 43
Phenylarsine oxide, 116
Phenylbutazone, 117
Phenytoin, 13
Phi toxin, 113
Phlebitis, 72
Phlesch Bubble Productions, preface
Phlogistic, 36
Phoenix, Christopher J., preface
Phosphatidylcholine (PC), 15, 33, 57, 85, 120
Phosphatidylethanolamine, 15
Phosphatidylinositol 3?kinase (PI3K), 115, 116, 117
Phosphatidylinositol 4?phosphate 5?kinase, 115
Phospholipase A2, 113, 119
Phospholipase A2 inhibitor, 113
Phospholipase C, 118, 119
Phospholipid, 15, 38, 45, 57, 84, 115, 118, 120, 139, 146
Phosphorylation, 59, 115, 116, 117, 131
Phosphorylcholine, 15, 24
Phosphotyrosine, 116
Photodynamic therapy, 85
Photopheresis, 30
Phytis, 51, 52, 54
Phytis diamond stent, 53
Phytohemagglutinin (PHA), 31
Phytotoxin, 1
Pica, 3
Picha, G.J., 17
Pierce, Daniel W., 151
PIF, 113, 115
Pig, 6, 44, 53, 55, 57, 59, 61, 62, 64, 65, 68, 70, 74, 77, 81, 94, 99, 106,
107, 108, 109, 132, 156, 160, 161
Pig blood, 44
PIM, 101
PIMP, 101
Pineal gland, 87
Pinealocyte, 160
Pinkerton, Sandra, preface
Pinkhassik, Eugene, preface, 50, 52, 57, 60, 69, 85
Pinocytosis, 66, 86
Pizzoferato, A., 80
PKA, 131
PKC, 131
PLA, 14, 17, 24
Placenta, 28, 32, 33, 51, 99
Plague, 34
Planktonic (cell), 11
Plasma cell (plasmacyte), 21, 26, 66, 73, 95
Plasmapheresis, 31
Plasmatic layer(/zone), 111, 141
Plasmid?based gene delivery vector, 85
Plasmin, 13, 23, 24, 38, 123
Plasminogen, 38, 75, 140
Plasminogen binding site, 140
Plasmodium falciparum, 34, 35, 120, 161
Plastic, 3, 4, 8, 10, 55, 64, 70, 72, 109, 160
Plastizyme, 19
Platelet, 4, 7, 12, 13, 14, 15, 23, 28, 29, 35, 36, 37, 38, 39, 41, 45, 49,
51, 52, 58, 62, 63, 64, 66, 67, 69, 70, 71, 79, 102, 116, 121, 125, 128, 131,
132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 146, 147, 159, 160
Platelet activating factor, 28, 36; see also PAF
Platelet adhesion, 7, 13, 14, 15, 38, 39, 49, 52, 58, 70, 79
Platelet aggregation, 39, 62, 139, 140, 147, 159
Platelet?derived growth factor, 45, 160
Platelet?endothelial cell adhesion molecule-1, 116; see also PECAM-1
Platinum, 68, 72, 83, 85, 135
Playing the drums, 138
Plectin, 150
Pledget, 71
Pleocytosis, 45
PLG, 105
PLGM, 17
Pliny the Elder, 1
Plug flow, 132
Plumbago, 5
Pluronic surfactant, 14
PMA, 120
PMMA, 17, 53, 54, 55, 99, 101, 104, 122
PMMA particle, 99, 104
PMN, 53, 98, 99, 100, 106, 107, 111, 113, 114, 115, 116, 120, 140, 141, 142
Pneumoconiosis, 2, 4, 5, 6
Pneumocystis, 35
Pneumonia, 34, 95, 117
Pneumothorax, 44
Poiseuille, 128
Poiseuille’s space, 141
Pollen, 4, 40, 41, 42
Poloxamine, 103
Poly?L?lysine, 17, 110
Poly(carbonate urethane), 17
Poly(ethylene glycol), 11, 13, 14, 15, 17, 59, 60, 85, 114
Poly(ethylene oxide) (PEO), 14, 24, 84
Poly(hydroxybutyrate), 70
Poly(inosinic acid), 116
Poly(lactic acid) (PLA), 14, 17, 24
Poly(N?isopropylacrylamide?co?N?n-butyl-acrylamide, 17
Poly(propylene oxide) (PPO), 14
Polyacrylamide, 17, 101
Polyacrylonitrile, 13
Polyadamantane, 54
Polyalkylsulfonated C60, 58, 59, 61
Polyamine, 14, 58, 113, 139
Polycythemia, 128, 158
Polyethylene, 8, 9, 11, 13, 14, 15, 17, 39, 54, 58, 71, 76, 77, 78, 79, 80,
84, 107, 110, 139
Polyethylene glycol, 11, 13, 58, 84, 139
Polyethylene terephthalate (Dacron), 17, 63, 70, 71, 132
Polyethylenimine (PEI), 85
Polyglucosan bodies, 160
Polyimide, 85
Polylactic?polyglycolic acid copolymer, 9
Polymer fume fever, 45, 73
Polymersome, 14
Polymorphonuclear leukocyte, 6, 33, 53, 67, 70, 73, 98, 99, 140, 160
Polyols, 143
Polypropylene, 15
Polysaccharide, 10, 14, 15, 19, 20, 23, 31, 34, 40, 88, 89, 114, 117, 144, 155
Polystyrene particle, 100, 104, 107, 114, 115
Polysulfone, 13
Polysulphone, 70
Polytef, 73, 74
Polytetrafluoroethylene (PTFE), 15, 17, 28, 68, 70, 72, 123
Polyurethane (PU), 11, 14, 15, 17, 39, 58
Polyvinylpyrrolidone (PVP), 46, 57, 59
Pope Clement VII, 1
Pope Paul II, 2
Porcine, 9, 63, 120, 160
Porins, 57, 148
Porosity, 10, 17, 47, 68, 72
Porphyromonas gingivalis, 22, 79
Portal blood, 105
Porter, R.E., Jr., 106
Post?apoptotic, 82
Potassium, 74, 150, 153
Potassium permanganate, 74
Potato, 41
Poxvirus, 34
PPA, 77
Prater, Michael, preface
Precambrian, 56
Prednisolone, 30
Prednisone, 30
Prekallikrein, 36, 38
Presentation semaphore, see Semaphore
Pressure ulcers, 125, 126, 133
Primaquine, 117
Primary ciliary dyskinesia, 151
Prionosis, 153
Progesterone, 59, 88
Programmed cell death, 120, 153
Prokaryotic cell, 46, 57
Proliferation inhibitor, 131, 132
Proliferation promoter, 131
Propane, 122
Properdin, see Factor P
Proplast, 71, 72, 86
Propranolol, 13
Prostacyclin, 39, 40
Prostaglandin, 28, 35, 36, 40, 45, 46, 70, 115, 125, 130, 131, 136
Prostate, 32, 135
Protease, 25, 28, 29, 34, 36, 38, 41, 59, 60, 98, 120, 149, 150, 160
Protein A, 28, 32, 34, 66, 115
Protein adhesion, 13, 50
Protein adsorption, 12, 13, 14, 15, 16, 17, 49, 51, 62, 63, 68, 69, 70, 75
Protein adsorption on alumina and sapphire, 75
Protein adsorption on diamond surface, 49
Protein adsorption on Teflon surfaces, 68, 69
Protein binding site, 13
Protein C, 40
Protein C inhibitor, 40
Protein G, 32
Protein kinase A (PKA), 131
Protein kinase C (PKC), 116, 131
Protein S, 40, 76
Proteoglycan, 17, 39, 136, 146
Proteolysis, 13, 23, 24, 35, 38, 40, 69, 145, 153
Proteolytic enzyme, 13, 23, 40, 69
Proteophilic, 76
Proteophobic, 13, 76, 102
Prothrombin, 32, 38, 39, 63, 67
Protozoa, 22, 23, 31, 35, 83, 98, 112, 119, 136, 144, 161
Pruritogen, 125
Pruritus, 125
Pseudomonas aeruginosa, 10, 11, 25, 29, 117, 119, 120, 160
Pseudomonas stutzeri, 160
Pseudorabies virus, 25
Psychogenic, 43
Psychosomatic, 128
PTD, 87
PTFE, 15, 17, 28, 68, 70, 72, 123
PU, 58
Puri, P., 74
Purine, 30
Purkinje neurons, 159
Putrescine, 113
PVA, 17
PVC, 11, 157, 158
PVP, 57, 59
Pyoinflammatory disease, 88
Pyrexia, 44
Pyrogen, 7, 36, 44, 45, 46, 122, 153
Pyrolite, 62, 63
Pyrolytic carbon, 8, 9, 36, 38, 46, 62, 63, 64, 78, 89, 142
Pyrolytic graphite, 14, 15
Pyropoikilocytosis, 138
Pyrrolidine, 58
Pyuria, 104
Q
Qi, Y., 31
Quantum dots, 29, 83, 84
Quartz, 50, 56, 58, 108
Qui, Yongxing, 15
Quin 2?AM, 130
R
Rab11, 118
Rabbit, 28, 33, 36, 51, 54, 58, 59, 62, 63, 64, 65, 66, 67, 70, 72, 73, 74,
77, 78, 80, 81, 83, 86, 89, 97, 104, 115, 118, 130, 148, 153, 156, 158, 159,
160
Rabbit blood, 51
Rac1, 116
Rader, C.P., 80
Radioimmunoassay, 24
Radioimmunotherapy, 85
Radiolabeled, 57, 93, 94, 101, 123
Radon, 4
Randall, John N., preface
RANTES, 118
Rao, Anil K., preface, 47
Rapamune, 132
Rapamycin, 30, 132
Rash, 40
Rat, 5, 6, 14, 17, 31, 36, 37, 46, 47, 52, 55, 56, 57, 58, 59, 60, 61, 62, 63,
65, 66, 67, 68, 70, 73, 77, 78, 79, 80, 81, 83, 84, 85, 86, 87, 94, 96, 97,
98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 113, 115,
120, 121, 123, 126, 127, 133, 134, 136, 142, 146, 147, 149, 152, 153, 155, 156,
157, 158, 159, 160
Ratner, B.D., 13, 19
Rawstern, Rocky, preface
RBC (red blood cell), see erythrocyte
Rck, 25
Receptor aggregation, 116
Reconfigurable binding site, 19
Red blood cell (RBC), see erythrocyte
Red cell aggregation, 142
Reduction of vascular permeability by nanoaggregates, 135
Reference human male, 155, 157
Reflex sympathetic dystrophy (RSD), 126
Reifman, Edward M., preface
Rejection, 7, 16, 29, 30, 32, 33, 41
Relapsing fever, 34
Renal shunt, 97
Rensselaer Polytechnic Institute, 56
Renwick, L.C., 68
Replicator, 162
RES, see Reticuloendothelial system
Resealing, 128, 146, 147, 148, 151
Resident transmembrane penetrators, 148
Resorption, 63, 77, 111, 156, 157
Respiratory burst, 70, 98
Respirocyte, 44, 120, 158, 162
Restenose, 131
Restenosis, 132
Reticulocyte, 95
Reticuloendothelial system (RES), 15, 65, 66, 79, 98, 99, 100, 102, 103, 105,
114, 116, 120, 121, 122
Retina, 32, 33, 66, 67, 72, 85, 94, 104, 105, 149, 159
Retinal ganglion cell (RGC), 85
Retinitis pigmentosa, 151
Retrofacial nucleus, 43
Retrovirus, 23, 31
Reuling, N., 77
Reverse diapedesis, 128
Reynolds number, 63
RGD, 13, 16, 17, 39, 110
RGDS, 17
RGE, 110
Rhabdoviridae, 60
Rheumatoid arthritis, 46
Rhinitis, 40, 41
Rho, 115, 116
Rho kinase, 116
Ribonucleic acid, see RNA
Ribosome, 78, 99, 123, 142, 143, 146
Ribotoxic, 120
Rice University, 55, 59
Ricin, 1
Rickettsia, 119, 161
Rifampin, 113
Rigidity, 56, 129, 139
Rimantadine, 28, 115, 120
RMP?7, 86
RNA, 23, 25, 82, 83, 123, 142, 149, 152
RNA polymerase, 152
RNAi, 83
Roberts, J.C., 84
Rodrigo, A.M., 80
Rogers, Carolyn, preface
Rolling adhesion, 13
Rootenberg, John D., preface, 39
Rosai?Dorfman disease, 161
Rose, Jillian, preface
Rosenberg, Lawrence, preface
Rostoker, W., 68
Rotavirus, 149
Rotor affinity, 146
Rotor binding site, 41, 87, 146
Rotor rim velocity, 145
Rotor?dejamming protocol, 146
Roughage, 126
Rouleaux, 139, 143, 144
Roxithromycin, 115
RSD (reflex sympathetic dystrophy), 126
Rubber, 41, 70, 155
Rubor, 35
Ruby, 75
Ruegsegger, M.A., 15
Ruffini ending, 126
Rugosity, 49, 51, 61, 138
Ruoslahti, E., 84
Russell bodies, 66
Ryanodine, 130, 131
S
S?protein (vitronectin), 16, 25, 50, 69, 75
SA, 77
Saccharide, 16, 17, 86
Saccharomyces cerevisiae, 115
Sagman, Uri, 60, preface
Saliva, 27, 34, 45, 79
Salmonella typhi, 117
Salmonella typhimurium, 25, 34, 46, 57, 119, 121
Salt particle, 4
San Joaquin Delta College Electron Microscopy Center, preface
Sandblasting, 133
Sanderson scale, 50
Sano, Y., 128
Sapphire, 6, 8, 13, 23, 24, 28, 29, 36, 38, 41, 45, 46, 49, 75, 76, 77, 78,
79, 80, 81, 88, 89, 91, 108, 109, 122, 142, 145
Sapphire dental implant, 75, 76, 78
Sapphire dust, 109
Sapphire particle, 75, 79, 80, 81, 108
Saprophyte, 34
Sarcolemma, 150
Sarcoma, 47, 51, 116
Sarcoptes scabiei, 125
Sarkar, D., 75
Sarkar, Niladri Neil, preface
Satulovsky, J., 17
Savinase, 69
Scabies, 125
Scanning electron microscope, 2, 51, 62, 78; see also SEM
Scanning tunneling microscope, see STM
Scar, 5, 19, 47, 55, 64, 74, 103, 110, 111, 160
Schaldach, M., 144
Schirrmacher, Frank, preface
Schistocyte, 138
Schistocytosis, 138
Schistosoma mansoni, 25
Schistosome, 33, 146
Schistosomiasis, 33
Schizont, 161
Schlemm’s canal, 104
Schleyer, Titus L., preface
Schmaier, Alvin H., 37
Schmidt, J.A., 6, 54
Schwann cell, 85
Scission, 112, 117, 149
Sclerosis, 61, 63, 86, 149, 152
Scopolamine, 43
Scott, M.D., 31
SDS, 49
Sea urchin, 14, 147
Seal, R.M., 108
Seaton, A., 123
Secretagogue, 112, 118, 123
Secretin, 125
Seeman, Nadrian C., preface, 81, 82
Seifert, J., 106
Selectin, 63, 79, 85, 136, 140, 141
Selectin antagonist, 85
Selectin binding site, 140
SEM, 2, 3, 4, 51, 58, 63, 72, 76, 81; see also scanning electron microscope
Semaphore, 14, 18, 29, 88, 89, 119, 122, 148
Semaphorin, 112, 113
Semiconductor particle, 84
Semiconductors, 81, 83
Seminal plasma, 40
Semliki Forest virus (SFV), 60
Sensitivity reaction, 40
Sepsis, 1, 25, 43, 44, 45, 97, 123, 140
Septic shock, 43, 44, 45, 140
Septicemia, 25
Serotonin, 28, 38, 40, 41, 42, 43
Serratia marcescens, 29
Sertoli cell, 33
Sessile bacteria, 11
Set point, 44, 45, 46
Shanghai Institute of Traumatology and Orthopedics, 81
Shape memory material, 83
Shapiro Syndrome, 45, 87
Shear force, 19, 42, 43, 76, 126, 130, 132, 133, 137, 138, 139, 140, 141, 143,
148
Shear stress, 11, 129, 130, 133, 134, 136, 137, 138, 139, 140, 141, 142, 143,
150
Sheep, 31, 52, 62, 64, 101, 102, 107, 114, 121, 133
Shigella flexneri, 34, 118, 119, 120, 161
Shivering, 42
Shock wave, 45, 56, 87, 145, 152
Shope virus, 34
Shungite, 56
Sialic acid, 24, 25, 84, 114, 145
Sialolithiasis, 45
Sialylation, 25
SiC, 49, 53, 54
Sickle cell, 95, 149
Silica, 3, 4, 5, 12, 15, 28, 36, 41, 45, 53, 64, 83, 87, 100, 107, 108, 109,
116, 138, 160
Silica particle, 5, 87, 107, 109
Silicographitosis, 5
Silicon, 4, 9, 18, 28, 49, 50, 51, 53, 61, 63, 69, 79, 83, 84, 85, 89, 148
Silicon dioxide, 4, 85
Silicone, 11, 15, 17, 70, 74, 86, 132, 136
Silicosis, 4
Silicotic nodule, 5
Silk fibroin, 88
Silver, 11, 17, 68, 78, 83, 85, 109, 132, 160
Silzone, 11
Simon, L., 106
Single?walled carbon nanotubes (SWNT), 28, 56, 59, 61; see also nanotube and
fullerene
Singlet oxygen, 46, 56, 57, 60, 88, 98
Sinusoid, 66, 94, 95, 96, 99, 102, 103, 108, 116
SiO2, 9, 51, 52, 79
Sirolimus, 30, 132
Skalak, R., 152
Skin cells, 9, 147
Sleep, 45, 157
Slime, 10, 13, 14, 115, 117
Small particle, 8, 95, 99, 105, 107, 109, 111, 117
Small particle disease, 109
Smalley, Richard E., 55, 56
SMC, 129, 130, 131, 132, 133
SME, 83
Smigrodzki, Rafal, preface, 127, 135, 137
Smith, Steven S., preface
Smog lung, 5
Snap?25, 147
Sneezing, 40, 42, 125
Snipes, M.B., 107
Sodium, 9, 29, 36, 49, 54, 74, 113, 131, 153, 158
Sodium dodecylsulfate (SDS), 29, 49
Sodium salicylate, 131
Somatic intrusiveness, 155, 157
Sorboregulatory, 18, 19, 24, 76
Soreff, J., 88
Sorting rotor, 19, 25, 29, 36, 37, 39, 41, 42, 44, 46, 87, 88, 89, 110, 119,
126, 134, 142, 143, 145, 146, 153
Southwest Research Institute, 8
Spallek, Heiko, preface
Specific (acquired) immune response, 20
Spectrin, 150
Sperm, 71, 123, 161
Spermatozoa, 144
Spermicide, 112
Spermidine, 113
Spermine, 139
Spherocyte, 95
Spherocytic hereditary elliptocytosis, 138
Sphingomyelin, 15
Spider legs, 4
Spinal, 7, 10, 42, 65, 93, 105, 125, 152, 156
Spine, 14
Spinothalamic tract, 125
Spira, Thomas J., 22
Spire Corp., 11, 13
Spirochete, 22, 34
Splanchnodynia, 155
Splanchnomegaly, 155
Spleen, 14, 22, 30, 31, 32, 59, 67, 73, 74, 79, 93, 94, 95, 96, 97, 99, 100,
101, 102, 103, 105, 106, 107, 108, 109, 112, 114, 121, 123, 142, 156, 157
Spleen vasculature, 95, 103
Splenectomy, 95, 97, 138
Splenofenestral motility, 96
Splenomegaly, 103, 109, 121, 156
SPM (suspended particulate matter), 4
Sporozoite, 120
Sprintz, Michael, preface, 1, 13, 29, 31, 66, 129, 157
SRBC, 102
St. Jude Medical, 11
Staerz, U.D., 31
Stainless steel, 47, 51, 52, 54, 68, 83, 85, 86, 90, 110, 132
Stall load, 151
Stanton, Mearl F., 47
Stanton hypothesis, 47
Staphylococcus aureus, 10, 11, 14, 22, 32, 34, 70, 96, 113, 114, 115, 120, 158
Staphylococcus epidermidis, 10, 11, 14, 71, 115
Staphylococcus intermedius, 120
Staphylothrombin, 32
STAR Inc., 9
Starburst, 84
Starch, 45, 158, 159
Starzl, T.E., 31
State University of New York, Stony Brook, 9
Staurosporine, 115, 117
Steal syndrome, 98
Stealth drug carrier, 114
Stealth liposome, 14, 15, 101
Stealth nanoparticle, 114
Stem cell, 30, 33, 132, 143
Stenosis, 72, 73, 74, 132, 134
Stenotic, 138
Stenotrophomaonas maltophilia, 144
Stent, 7, 9, 10, 11, 38, 51, 52, 53, 54, 72, 129, 130, 131, 132, 133, 134, 135,
138, 142
Steps and grooves, 18
Stercoral, 126
Stereocilia, 131
Steric hindrance, 122
Steric repulsion, 14, 15
Sternutation, 40, 42
Sternutogenesis, 42
Stiffness, 47, 63, 135, 151
STING, 74
STM (scanning tunneling microscope), 61, 62
STOC, 130
Stomach, 1, 2, 4, 42, 57, 59, 106, 126, 127, 149, 155, 156, 157
Storage disease, 87, 159
Streilein, J. Wayne, 32
Streptococcal, 25, 113, 114, 117, 144
Streptococcus mutans, 34, 79
Streptococcus pneumoniae, 34, 95, 117
Streptococcus pyogenes, 32, 34, 60, 113, 114, 117, 120
Streptolysin O, 113, 120
Stretch forces, 127, 130
Stretch?activated channel, 131, 143
String test, 3
Stryer, Lubert, 26
Stuhlmeier, K.M., 31
Stump, M.M., 132
Stylosome, 127
Subcutis, 59, 79, 105
Substance P, 125
Subtilisin, 69
Suicide sacs, 149
Sulfalipid, 119
Sulfapyridine, 75
Sulfatide, 119
Sulfonamide, 41
Sultan Bejazet II, 1
Superantigen, 21
Superoxide, 53, 59, 67, 70, 98
Suramin, 119
Surface adhesion, 49
Surface electrical thrombogenicity, 143, 145
Surface free energy, 16, 69, 79
Surface wettability, 16, 50, 52
Surface?dwelling bacteria, 34
Surfactant, 4, 14, 15, 29, 49, 75, 103, 115
SurModics Inc., 13
Suture, 8, 9, 10, 68, 71, 93, 109, 133
Swab, 109
SWAP, 33
Sweat, 27, 90
Swim races, 138
Swimmer’s hemolysis, 138
Swine, 149
Switchable surface, 19
SWNT (single?walled carbon nanotubes), 28, 56, 59, 61
Syk, 116
Symbiont, 119
Symbiosome, 119
Sympathomimetic, 41
Synaptobrevin, 118, 147
Syncope, 128, 129
Synechia, 72
Synovial fluid, 8, 45, 156
Synoviocyte, 45
Syntaxin, 118
Systemic lupus erythematosis (SLE), 82
Systemic phagocytic blockade, 121
Systolic, 35, 128, 129
T
T cell, 21, 22, 29, 30, 31, 33, 88, 89, 103, 118, 120, 136, 144
T cells, 20, 21, 30, 31, 32, 33, 34, 45, 86, 88, 89, 106, 120, 136, 137
T lymphocyte, 21, 22, 23, 31, 33, 41, 100, 107, 120, 141
T?2 toxin, 115
T?suppressor, 30
T.G. Wilson, 127
T4 (bacteriophage), 15, 114, 161
Tabata, Y., 105
Tachyphylaxis, 46
TACO, 119
Tacrolimus, 30
Tagatose, 89
Talc, 5, 109
Tamponade, 133
Tandy, Charles, preface
Tang, L., 49, 50, 51
Tantalum, 9, 85, 108, 134
Tardigrade, 143
Tattoo, 41, 53, 64, 65, 66, 105, 110
Taurine, 112
Taxane, 132
Taxol, 60
Tay?Sachs disease, 159
TBLN, 107
TCPS, 79
Tears (fluid), 27
Technegas particle, 4
Technetium, 4, 101
Technological intrusiveness, 155, 161
Teflon, 4, 8, 10, 15, 23, 28, 36, 38, 41, 45, 46, 49, 68, 69, 70, 71, 72, 73,
74, 75, 78, 86, 88, 89, 93, 106, 107, 109, 123, 132, 134, 138, 141, 142; see
also fluorocarbon polymer
Teflon fever, 45
Teflon particle, 4, 41, 46, 68, 69, 72, 73, 74, 75, 86, 106, 107, 109
Teflon paste, 73, 74, 93
Teflonoma, 74
Teicoplanin, 113
Telomere, 47
TEM, 4, 69; see also transmission electron microsope
Tenascin, 16
Tenase complex, 38
Tensegrity, 149
Terabot (nanorobot dose), 44, 89, 90, 120, 137, 138, 146, 154
Teratogenicity, 7, 46, 57
Terra, Richard P., preface
Testis, 32, 33
Tetracycline, 113, 115
Tetraethylammonium (TEA), 130
Tetraethylene glycol dimethyl ether, 13
Tetrafluoroethylene, 46, 69, 70, 72
Tetrahymena, 112, 152
Tetrahymena pyriformis, 112, 152
Tetrahymena thermophila, 112
Tetraphenylboron, 112
TGF?b, 32, 33, 60, 130, 131
TH1, 29, 31
TH2, 31
Thapsigargin, 136
Thermal conductivity, 75, 89, 90, 91
Thermocompatibility, 89
Thermogenic limit, 44, 89
Thionychloride, 58
Thomas G. Wilson, preface, 76
Thomas Lucas Productions, preface
Thompson, N.G., 68
Thomson, L. Anne, 51
Thorn, 109
THP, 66, 69, 80
Threonine kinase, 115
Thrombin, 38, 39, 40, 63, 131
Thrombocyte, see platelet
Thrombocytolysis, 139, 140
Thrombocytopenia, 38, 39, 67
Thromboemboli, 8, 38, 40, 67, 134
Thrombogenesis, 7, 39, 52, 70, 79, 123, 128
Thrombogenicity, 9, 13, 37, 38, 51, 52, 62, 70, 78, 132, 143, 145
Thrombomodulin, 40
Thromboplastin, 24, 38, 40, 67
Thrombosis, 7, 8, 12, 13, 39
Thrombospondin, 16, 79, 131
Thrombotic thrombocytopenic purpura (TTP), 138
Thymocyte, 21, 54, 144
Thymus, 21, 30, 31, 99, 103, 107
Thyroglobulin, 58
Ticlopidine, 40
Timasheff, S.N., 14
Timp, Gregory L., 84
Tin, 5, 103, 109
Tin particle, 109
TiNi, 83
TiNi particle, 83
Tinkle, Sally S., 127
Tinschert, J., 76
Tissue adhesion, 10
Tissue cell, 10, 17, 70, 100, 125, 135, 136, 137, 142, 146, 147, 149, 150, 151,
153, 159, 160
Tissue compression, 134
Tissue culture test, 11
Tissue is burdened, 161
Tissue pathway factor inhibitor (TPFI), 40
Tissue plasminogen activator (tPA), 38, 140
Tissue response to bulk alumina and sapphire, 77
Titania (titanium dioxide), 51, 52, 79, 83, 127
Titanium, 8, 9, 10, 18, 51, 63, 65, 68, 75, 76, 77, 78, 79, 83, 86, 110, 111,
127
TLR, 22
TLV, 66
TMJ, 71
TNF, 16, 20, 21, 31, 43, 45, 46, 69, 80, 118, 131, 134; see also tumor necrosis
factor
Tobramycin, 86
Todar, 33, 34
Togaviridae, 60
Tolerization, see immune system
Tolerogen, 31
Tomalia, Donald A., 84
Toni, A., 81
Toniolo, C., 59
Tooth amoeba, 99
Tophi, 156
Topography, 10, 18, 51
Topotecan (topoisomerase I inhibitor), 131, 132
Tortuosity, 90
Total Artificial Heart (TAH), 10
Total lymphoid irradiation (TLI), 30, 122
Toth?Fejel, Tihamer, preface
Toxic shock, 21
Toxicity, 1, 3, 4, 5, 6, 7, 11, 51, 54, 55, 56, 57, 58, 59, 60, 61, 65, 66,
68, 73, 78, 80, 81, 82, 83, 84, 85, 86, 94, 97, 105, 106, 120, 123, 157, 158
Toxicology, 2, 3, 47, 54, 55, 56
Toxin B, 115, 116
Toxins, 21, 36, 43, 45, 88, 113, 115, 119, 120
Toxoplasma gondii, 34, 35, 119
Trabecular, 33, 64, 104, 108, 115, 153
Traditional medical implants, 7
Transcytosis, 84, 86
Transendothelial migration, see diapedesis
Transendothelial penetration, 128
Transepithelial penetration, 127
Transferrin, 16, 118
Transit time, 67, 96, 129, 147
Transmembrane integral protein, 148
Transmembrane ion channel, 148
Transmembrane penetrator, 148
Transmission electron microscope, 64, 76, 78, 147; see also TEM
Transmyocardial mechanical revascularization, 37
Trehalose, 119, 143
Trehalose glycolipid, 119
Treponema pallidum, 32, 114, 117
Tricalcium phosphate, 9, 41
Trichomonas vaginalis, 112
Trifluoperazine, 115
Triosite, 41
Tromantadine, 54
Trophozoite, 43
Tropisetron, 43
Tropomyosin, 116
Trowbridge, Henry O., 22, 37
Trump, B.F., 123
Trypanosoma cruzi, 23, 25, 119
Trypanosome, 23, 34
Trypsin, 23, 24, 38, 41
Tryptase, 41, 42
Tse, R.L., 53, 54
Tuberculosis, 9, 31, 34, 35, 41, 60, 110, 113, 119, 161
Tuberculosis bacterium, 161
Tubocurarine, 86
Tubulin, 82, 150
Tumor (inflammation), 35; see also Inflammation
Tumor necrosis factor, 20, 21, 43, 45, 60, 80, 113, 160; see also TNF
Tumorigenic, 7, 46, 47
Tumors, 6, 7, 17, 20, 22, 24, 32, 33, 34, 35, 43, 44, 46, 47, 52, 54, 57, 59,
60, 67, 72, 73, 74, 84, 85, 86, 101, 137, 157, 160, 161
Tungsten, 5, 6, 85, 104
Tungsten particle, 5, 104
Turbulence, 4, 12, 111
Turnover rate, 146, 153
Turnover time, 103, 146
Typhus, 161
Tyrosine kinase, 59, 115, 116, 130
Tyzzer, 161
U
U.S. Pharmacopoeia, 158
Ubiquitin, 113, 153
Ulcer, 9, 110, 125, 126, 127, 133
ULTI, 62, 63
Ultrafiltration, 128, 135
Ultramet, 13
Ultrasound, 11, 131, 134, 153, 158
Umbilical, 131, 138, 140
University of Bologna, 81
University of Edinburgh, 10
University of Maryland Biotechnology Institute, 143
University of Michigan, 84
University of Montpellier, 55
University of Nevada, Reno, 69
University of Sheffield, 9
University of Tennessee, Knoxville, 69
University of Tokushima School of Medicine, 77
University of Vermont College of Medicine, 55
University of Washington, 16, 19
Unmyelinated, 125
Urate, 23, 24, 28, 36, 38, 45, 53, 54, 156
Urease, 25
Uremia, 43
Urinary incontinence, 68, 74, 107
Urine, 17, 54, 59, 74, 104, 122, 138
Urokinase, 38
Urolithiasis (bladder stones), 45
Urticaria, 40, 41
Uterine, 133, 146, 156, 157
Uteroglobin, 113
Uterus, 32, 57, 59, 156
UTP, 147
UVB, 60
Uveitis, 156
V
Vaccine, 40, 80, 85, 123
Vaccinia, 46
Vacuole, 5, 34, 66, 98, 101, 102, 104, 105, 107, 112, 117, 118, 119, 120, 141,
160
Vagabond’s disease, 127
Vagina, 104
Vagrant’s disease, 127
Vale, Ronald D., 151
Valsalva, sinuses of, 97
VAMP, 118
Van der Waals forces, 76, 145
Van Nedervelde, Philippe, preface
Varde, M., 18
Varix, 138
Vasa vasorum, 132
Vascular collapse, 41
Vascular destruction, 134
Vascular dissection, 133, 134
Vascular gate, 97
Vascular leak, 128, 135
Vascular mechanocompatibility, 129
Vascular obstruction, 9, 132, 135
Vascular response to stenting, 131
Vasculitis, 41, 82, 133, 138
Vasculoid, 90, 131, 135
Vasculomobile nanorobot, 97, 131, 141, 142
Vasculomobility, 97, 110, 129, 130, 131, 133, 138, 141, 142
Vasculopathy, 132, 133, 134
Vasoconstrictor, 41
Vasodilation, 24, 28, 35, 40, 43, 97
Vasopressin, 46
Velopharyngeal incompetence, 74
Venoms and insect stings, 40
Venous blood, 67, 71, 94, 126, 141, 142
Vermipodia, 118
Vero (cell), 60
Vertigo, 43
Vesicle, 24, 58, 84, 116, 117, 118, 119, 123, 139, 144, 146, 147, 148, 149,
150, 151, 152, 160
Vesicoureteric reflux, 74, 107
Vesicular stomatitis virus (VSV), 60
Veto effect, 31
Vi (K) antigen, 117
Vibration white finger, 138, 141
Vibrio alginolyticus, 112
Vibrio cholerae, 34, 143
Vimentin, 136, 152
Vinblastine, 118
Vincristine, 150
Vinculin, 78, 116
VIP (vasoactive intestinal polypeptide), 113, 115
Virosome, 16
Virucide, 120
Virus, 4, 8, 16, 20, 21, 22, 23, 24, 25, 28, 31, 32, 34, 35, 45, 46, 60, 83,
84, 86, 108, 112, 114, 119, 123, 129, 143, 147
Virus particle, 84, 121
Visceral torsion, 44
Vitamin A, 149
Vitamin D, 80, 123
Vitamin E, 61
Vitamin K, 40
Vita?More, Natasha, preface
Vitek Research Corp., 13
Vitreous carbon, 36, 61, 62, 77
Vitri?dried cells, 143
Vitronectin, 16, 25, 50, 69, 75
Vocal cord paralysis, 73
Volvulus, 44
Vomiting, 40, 42, 43, 87, 158
Von Ehr, James R., II, preface
Von Willebrand’s factor, 38
VR, 126
Vroman effect, 13, 14
Vroman, Leo, 12
VUR, 74
W
Waldenstrom’s macroglobulinemia, 158
Wang, Z.X., 81
Ward, C.A., 89
Warfarin, 39, 52
Warner. A., 101
Water intoxication, 158
White blood cell (WBC), see leukocyte
Wear particles, 8, 12, 52, 64, 65, 66, 77, 79, 93, 107, 111, 122
Weber, David O., preface
Weiner, Michael, preface
Weisman, R.B., 56
Weiss, Leon, 96
Wettability, 16, 17, 19, 50, 52, 75, 101
Wheat germ agglutinin, 139
Wheelchair, 126
WBC (white blood cell), see leukocyte
Whitesides, George M., 14
Whole blood, 12, 39, 41, 79, 89, 157, 158
Wiley, Christopher, preface, 128, 133
Wilkinson, 18
Willert, 109
Wilson, Lon J., 59
Wilson, Stephen R., preface
Wilson, Thomas G., 59
Wismar, B.L., 101
Wolbachia, 161
Wolber, Paul K., preface
Wood, 109
World Health Organization (WHO), 4
World Technology Network, preface
World Transhumanist Association, preface
Woronin body, 148
Wortmannin (WM), 117
Wounded, 147
Wounded cell, 147
Wowk, Brian, preface, 90
Wu, C.H., 58
X
X?ray diffraction, 75
Xenogeneic, 31, 32
Xenopus, 84, 137, 147, 153
Xu, Bai, preface
Y
YadA, 25
Yakutia, Russia, 6
Yeast particle, 106, 117
Yersinia enterocolitica, 25, 34, 115, 120, 121
Yersinia pestis, 117
Yoder, M.N., 50
Yop, 115, 120
Yoshida, K., 76
Young’s modulus, 110
Yudkowsky, Eliezer S., preface
Z
Zakharenko, L.P., 57
Zeiosis, 118
Zeta potential, 53, 145
Zhang, Yong, 137
Zinc, 45, 113
Zircon, 41
Zirconium, 8, 41, 52
Zirconium oxide, 8
ZnS, 29, 84
Zonula occludens, 142
Zr, 54, 68, 80
Zymogen, 23, 38
Zymosan, 103, 115, 123
Zymosan particle, 103, 115
Zyvex Corp., preface
Last updated on 30 April 2004